Transcriptomic responses of water buffalo liver to infection with the digenetic fluke Fasciola gigantica
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- 作者：Fu-Kai Zhang ; Xiao-Xuan Zhang ; Hany M. Elsheikha ; Jun-Jun He…
- 关键词：Fasciola gigantica ; Immunomodulation ; RNA ; sequencing ; Transcriptome ; Water buffalo
- 刊名：Parasites & Vectors
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：2758KB
- 刊物主题：Parasitology; Entomology; Tropical Medicine; Infectious Diseases; Veterinary Medicine/Veterinary Science; Virology;
- 出版者：BioMed Central
- ISSN：1756-3305
- 卷排序：10
文摘
BackgroundFasciola gigantica, the tropical liver fluke, infects buffaloes in Asian and African countries and causes significant economic losses and poses public health threat in these countries. However, little is known of the transcriptional response of buffaloes to infection with F. gigantica. The objective of the present study was to perform the first transcriptomic analysis of buffalo liver infected by F. gigantica. Understanding the mechanisms that underpin F. gigantica infection in buffaloes will contribute to our ability to control this parasite.