Human breast adipose tissue: characterization of factors that change during tumor progression in human breast cancer
详细信息 查看全文
- 作者：Sabrina Johanna Fletcher…
- 关键词：Human breast adipose tissue ; Breast epithelial cells ; Breast cancer ; Epithelial ; stromal interactions
- 刊名：Journal of Experimental & Clinical Cancer Research
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：36
- 期：1
- 全文大小：4729KB
- 刊物主题：Oncology; Cancer Research; Immunology; Apoptosis;
- 出版者：BioMed Central
- ISSN：1756-9966
- 卷排序：36
文摘
BackgroundAdipose microenvironment is involved in signaling pathways that influence breast cancer. We aim to characterize factors that are modified: 1) in tumor and non tumor human breast epithelial cell lines when incubated with conditioned media (CMs) from human breast cancer adipose tissue explants (hATT) or normal breast adipose tissue explants (hATN); 2) in hATN-CMs vs hATT-CMs; 3) in the tumor associated adipocytes vs. non tumor associated adipocytes.