Overexpression of suppressor of zest 12 is associated with cervical node metastasis and unfavorable prognosis in tongue squamous cell carcinoma
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- 作者：Huijun Hu ; Yi Wang ; Zhongwu Li ; Yumin Zhu ; Wei Zhang…
- 关键词：SUZ12 ; Polycomb repressive complex ; Tongue squamous cell carcinoma ; Prognosis
- 刊名：Cancer Cell International
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：1416KB
- 刊物主题：Cancer Research; Cell Biology;
- 出版者：BioMed Central
- ISSN：1475-2867
- 卷排序：17
文摘
ObjectiveIncreased expression of suppressor of zest 12 (SUZ12), a core component of the polycomb repressive complex 2, contributes to human tumorigenesis and associates with patient prognosis. In the present study, we sought to investigate the expression of SUZ12 and its clinicopathological significance in primary tongue squamous cell carcinoma (TSCC).