Green Synthesis of Iron Oxide Nanoparticles and Their Catalytic and In Vitro Anticancer Activities

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• 作者：P. C. Nagajyothi ; Muthuraman Pandurangan ; Doo Hwan Kim…
• 关键词：Green synthesis ; Iron oxide nanoparticles ; Psoralea corylifolia ; Catalytic activity ; In ; vitro anticancer activity
• 刊名：Journal of Cluster Science
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：1
• 页码：245-257
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Catalysis; Inorganic Chemistry; Physical Chemistry; Nanochemistry;
• 出版者：Springer US
• ISSN：1572-8862
• 卷排序：28

文摘

The green synthesis of nanoparticles is a convenient, inexpensive, rapid and eco-friendly method compared to traditional synthesis methods. We synthesized iron oxide nanoparticles (α-Fe₂O₃ (hematite)) nanoparticles from iron (III) chloride using an aqueous extract of Psoralea corylifolia seeds as a reducing agent. Various characterization methods indicate that nanoparticles were crystalline with an average size of ~39 nm. The nanoparticles were assessed for their catalytic activity on methylene blue using a UV–Vis spectrophotometer and showed a rapid reduction within 63 min. The in vitro anticancer activity of the nanoparticles was also determined by Sulforhodamine (SRB) assay, and caspase-3 expression was determined using caspase-3 fluorescence and immunofluorescence assays. The results were suggested the strong cancer cell growth inhibition in a dose-dependent manner.