Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort

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• 作者：Yu-Jun Chen ; Jennifer Anne Wambach ; Kelcey DePass…
• 关键词：genetic epidemiology ; human population genetics ; neonatal respiratory distress syndrome ; pulmonary surfactant
• 刊名：World Journal of Pediatrics
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：12
• 期：2
• 页码：190-195
• 全文大小：208 KB
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• 作者单位：Yu-Jun Chen (1) (2)
  Jennifer Anne Wambach (2)
  Kelcey DePass (2)
  Daniel James Wegner (2)
  Shao-Ke Chen (3)
  Qun-Yuan Zhang (4)
  Hillary Heins (2)
  Francis Sessions Cole (2)
  Aaron Hamvas (2) (5)
  
  1. Division of Neonatology, Department of Pediatrics, the First Affiliated Hospital of Guangxi Medical University, Nanning, China
  2. Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, USA
  3. Department of Pediatrics, Guangxi Maternal and Child Health Hospital, Nanning, China
  4. Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, USA
  5. Division of Neonatology, Ann and Robert H. Lurie Children’s Hospital, 225 E. Chicago Ave, Box No. 45, Chicago, IL, 60611, USA
  
• 刊物主题：Pediatrics; Pediatric Surgery; Maternal and Child Health; Intensive / Critical Care Medicine; Surgery; Imaging / Radiology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1867-0687

文摘

Background Rare mutations in surfactant-associated genes contribute to neonatal respiratory distress syndrome. The frequency of mutations in these genes in the Chinese population is unknown.