文摘
Objectives To compare oncological outcomes of a consecutive retropubic radical prostatectomy (RRP) and robot-assisted radical prostatectomy (RARP) series performed by a single surgeon who had performed >750 prior RRPs and was starting to perform RARPs. Materials and methods Prospectively collected longitudinal data of 277 RRP and 730 RARP cases over a 5-year period were retrospectively analyzed. The RARP series were divided into 3 subgroups (1st, <250 cases; 2nd, 250-00; and 3rd, >500) according to the surgical period. The positive surgical margin (PSM) and biochemical recurrence-free survival (BCRFS) rates were compared at each pathological stage. Results The pT2 PSM rates showed no significant difference between the RRP (7.8?%) and RARP series (1st, 9.5?%; 2nd, 14.1?%; and 3rd, 9.8?%) throughout the study period (P?=?0.689, 0.079, and 0.688, respectively). Although the pT3 PSM rates of the 1st (50.6?%) and 2nd RARP series (50.0?%) were higher than that of the RRP series (36.0?%; P?=?0.044 and P?=?0.069, respectively), the 3rd RARP series had a comparable pT3 PSM rate (32.4?%, P?=?0.641). The 3-year BCRFS rates of the RRP and RARP series were similar at each pathological stage (pT2, 92.1 vs. 96.8?%, P?=?0.517; pT3, 60.0 vs. 67.3?%, P?=?0.265, respectively). Conclusions The pT2 PSM and short-term BCRFS rates were similar between RRP and RARP, and RARP showed comparable pT3 PSM rate with RRP after >500 cases of surgical experience. Our data suggest that an experienced robotic surgeon at a high-volume center may achieve comparable oncological outcomes with open prostatectomy even in locally advanced disease.