An alternative nerve conduction study method to evaluate early diabetic neuropathy: Ratio of different diameter nerve fibers in peroneal nerve

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• 作者：Nedim Ongun ; Çağdaş Erdoğan ; Selma Tekin…
• 关键词：Diabetes mellitus ; Nerve conduction study ; Peroneal nerve
• 刊名：International Journal of Diabetes in Developing Countries
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：35
• 期：3-supp
• 页码：461-464
• 全文大小：226 KB
• 参考文献：1.Henneman E, Olson CB. Relations between structure and function in the design of skeletal muscles. J Neurophysiol. 1965;28:581–98.PubMed
  2.Koytak PK, Isak B, Borucu D, Uluc K, Tanridag T, Us O. Assessment of symptomatic diabetic patients with normal nerve conduction studies: utility of cutaneous silent periods and autonomic tests. Muscle Nerve. 2011;43(3):317–23.PubMed CrossRef
  3.Luo KR, Chao CC, Chen YT, Huang CM, Yang NC, Kan HW, et al. Quantitation of sudomotor innervation in skin biopsies of patients with diabetic neuropathy. J Neuropathol Exp Neurol. 2011;70(10):930–8.PubMed CrossRef
  4.Herrmann DN, Boger JN, Jansen C, Alessi-Fox C. In vivo confocal microscopy of Meissner corpuscles as a measure of sensory neuropathy. Neurology. 2007;69(23):2121–7.PubMed CrossRef
  5.Barnett C, Perkins BA, Ngo M, Todorov S, Leung R, Bril V. Sural-to-radial amplitude ratio in the diagnosis of diabetic sensorimotor polyneuropathy. Muscle Nerve. 2012;45(1):126–7.PubMed CrossRef
  6.Bae JS, Kim OK, Kim JM. Altered nerve excitability in subclinical/early diabetic neuropathy: evidence for early neurovascular process in diabetes mellitus? Diabetes Res Clin Pract. 2011;91(2):183–9.PubMed CrossRef
  7.Oğuzhanoğlu A, Güler S, Cam M, Değirmenci E. Conduction in ulnar nerve bundles that innervate the proximal and distal muscles: a clinical trial. BMC Neurol. 2010;10:81.PubMed PubMedCentral
  8.Gassel MM, Trojaborg W. Clinical and electrophysiological study of the pattern of conduction times in the distribution of the sciatic nerve. J Neurol Neurosurg Psychiatry. 1964;27:351–7.PubMed PubMedCentral CrossRef
  9.Johnsen B, Fuglsang-Frederiksen A, de Carvalho M, Labarre-Vila A, Nix W, Schofield I. Amplitude, area and duration of the compound muscle action potential change in different ways over the length of the ulnar nerve. Clin Neurophysiol. 2006;117:2085–92.PubMed CrossRef
  10.Oğuzhanoğlu A, Erdoğan Ç, Tabak E, Cenikli U. Comparison of conduction velocities of nerve fibers to smaller and larger muscles in rats. Int J Neurosci. 2010;120:76–9.PubMed CrossRef
  11.Kimura J, Sakimura Y, Machida M, Fuchigami Y, Ishida T, et al. Effect of desynchronized inputs on compound sensory and muscle action potentials. Muscle Nerve. 1988;11:694–702.PubMed CrossRef
  12.Kimura J, Machida M, Ishida T, Yamada T, Rodnitzky RL, Kudo Y, et al. Relation between size of compound sensory or muscle action potentials and length of nerve segment. Neurology. 1986;36:647–52.PubMed CrossRef
  13.Padua L, Stålberg E, Caliandro P, Muscogiuri G, Pazzaglia C, Sorice GP, et al. Single-fiber conduction velocity test allows earlier detection of abnormalities in diabetes. Muscle Nerve. 2011;43(5):652–6.PubMed CrossRef
  14.Mueller D, Obermann M, Koeppen S, Kavuk I, Yoon MS, Sack F, et al. Electrically evoked nociceptive potentials for early detection of diabetic small-fiber neuropathy. Eur J Neurol. 2010;17(6):834–41.PubMed CrossRef
  15.Erdoğan C, Yücel M, Değirmenci E, Öz O, Akgün H, Odabaşı Z. Nerve excitability properties in early preclinical diabetic neuropathy. Diabetes Res Clin Pract. 2011;94(1):100–4.PubMed CrossRef
  16.Altun Y, Demirkol A, Tumay Y, Ekmekci K, Unsal I, Koyluoglu AC, et al. The medial plantar and medial peroneal cutaneous nerve conduction studies for diabetic polyneuropathy. Neurol Sci. 2011;32(5):849–54.PubMed CrossRef
  17.Kimura J. Principles and pitfalls of nerve conduction studies. Ann Neurol. 1984;16:415–29.PubMed CrossRef
  18.Gilliatt RW, Sears TA. Sensory nerve action potentials in patients with peripheral nerve lesions. J Neurol Neurosurg Psychiatry. 1958;21:109–18.PubMed PubMedCentral CrossRef
  19.Raynor EM, Ross MH, Shefner JM, Preston DC. Differentiation between axonal and demyelinating neuropathies: identical segments recorded from proximal and distal muscles. Muscle Nerve. 1995;18:402–8.PubMed CrossRef
  
• 作者单位：Nedim Ongun (1)
  Çağdaş Erdoğan (2)
  Selma Tekin (2)
  Attila Oğuzhanoğlu (2)
  
  1. Department of Neurology, Denizli State Hospital, Denizli, Turkey
  2. Department of Neurology, Pamukkale University Hospital, Denizli, Turkey
  
• 刊物主题：Medicine/Public Health, general; General Practice / Family Medicine; Health Administration; Diabetes;
• 出版者：Springer India
• ISSN：1998-3832

文摘

Different nerve fibers may have disparate conduction parameters even though they are in the same peripheral nerve. Hyperglycemia can have differential effects on nerve fibers, depending on diameter. In diabetes, conventional nerve conduction studies have allowed us to classify a peripheral nerve as normal or not. But, there may be differential involvement in disparate nerve fibers of the same peripheral nerve. This study evaluated the effects of hyperglycemia on nerve fibers of peroneal nerve by diameter. Thirty-five diabetic patients with normal nerve conduction studies and thirty-two healthy controls were included to the study. The peroneal nerve was stimulated from two points (upper and below the fibula head) and recorded from the tibialis anterior (TA) and extensor digitorum brevis (EDB) muscles. Then the ratios of conduction velocity parameters recorded in these sides were compared between the diabetic and control groups. The conduction velocity recorded from EDB seemed to be faster in both groups. But there were no significant differences among the ratios between the groups. Our study has demonstrated the conduction parameters of two nerve fibers with different diameters in the peroneal nerve. The ratios of conduction parameters were similar in both groups, suggesting that fibers in the peroneal nerve are similarly affected by hyperglycemia.