The modeling of rat EEG signals in absence epilepsy in the analysis of brain connectivity
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- 作者：M. V. Sysoeva ; G. D. Kuznetsova ; I. V. Sysoev
- 关键词：absence epilepsy ; Granger causality ; time ; series modeling ; nonstationary signal ; nonlinear oscillations ; connectivity
- 刊名：Biophysics
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：61
- 期：4
- 页码：661-669
- 全文大小：758 KB
- 刊物主题：Biophysics and Biological Physics;
- 出版者：Springer US
- ISSN：1555-6654
- 卷排序：61
文摘
Simple models that describe some features of the electrical brain activity in rats with genetic absence epilepsy recorded before and after an epileptic seizure have been proposed in this study. These models can help to analyze the efficiency of the Granger causality analysis of the directional connectivity determination. The comparison of the results of the experimental and modeled signal analysis, on one hand, reveals a number of artifacts of this method, and on the other hand, proves its effectiveness in the research on absence epilepsy mechanisms.