Cyclophilin A Enhances Cell Proliferation and Xenografted Tumor Growth of Early Gastric Cancer

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• 作者：Wenhua Feng ; Yan Xin ; Yuping Xiao ; Wenhui Li ; Dan Sun
• 关键词：Cyclophilin A ; Gastric cancer ; ERK1/2 ; Proliferation ; Autophagy
• 刊名：Digestive Diseases and Sciences
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：60
• 期：9
• 页码：2700-2711
• 全文大小：4,346 KB
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• 作者单位：Wenhua Feng (1) (2) (3)
  Yan Xin (1)
  Yuping Xiao (1)
  Wenhui Li (1)
  Dan Sun (1)
  
  1. Department of Gastrointestinal Tumor Pathology of Cancer Institute and General Surgery Institute, The First Hospital of China Medical University, 155 Nanjing North Street, Heping District, Shenyang, 110001, China
  2. Key Laboratory of Reproductive Health and Medical Genetics, National Health and Family Planning Commission, Shenyang, China
  3. Key Laboratory of Reproductive Health of Liaoning, Shenyang, China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Gastroenterology
  Hepatology
  Oncology
  Transplant Surgery
  Biochemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-2568

文摘

Background Recently Cyclophilin A (CypA) was identified as a candidate target protein in gastric carcinoma. However, the role of CypA in gastric cancer (GC) has not been investigated extensively so far.