Haplotype of platelet receptor P2RY12 gene is associated with residual clopidogrel on-treatment platelet reactivity

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• 作者：Xiao-yan Nie ; Jun-lei Li ; Yong Zhang ; Yang Xu…
• 关键词：Key wordsP2RY12 ; CYP2C19 ; Haplotype ; Single nucleotide polymorphism (SNP) ; Clopidogrel ; Thromboelastography
• 刊名：Journal of Zhejiang University-SCIENCE B
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：18
• 期：1
• 页码：37-47
• 全文大小：
• 刊物主题：Biomedicine, general;
• 出版者：Zhejiang University Press
• ISSN：1862-1783
• 卷排序：18

文摘

ObjectiveTo investigate a possible association between common variations of the P2RY12 and the residual clopidogrel on-treatment platelet reactivity after adjusting for the influence of CYP2C19 tested by thromboelastography (TEG).