Establishment and characterization of a metastasis model of human gastric cancer in nude mice

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• 作者：Kesheng Li ; Huifen Du ; Xiaowen Lian ; Dandan Chai ; Xinwen Li ; Rong Yang…
• 关键词：Characterization ; Establishment ; Gastric cancer ; Metastasis ; Mouse models
• 刊名：BMC Cancer
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：3,579 KB
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• 作者单位：Kesheng Li (1)
  Huifen Du (1)
  Xiaowen Lian (1)
  Dandan Chai (1)
  Xinwen Li (2)
  Rong Yang (3)
  Chunya Wang (1)
  
  1. Department of Medicine Biotechnology, Medicine and Science Research Institute of Gansu province, Lanzhou, China
  2. Department of Surgery, Tumor Hospital of Gansu province, Lanzhou, China
  3. Department of pathology, Tumor Hospital of Gansu province, Lanzhou, China
  
• 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2407

文摘

Background A mouse model of metastasis of human gastric cancer is one of the most important tools for studying the biological mechanisms underlying human gastric cancer metastasis. In this paper, we established a mouse model of metastatic human gastric cancer in nude mice that has a higher rate of tumor formation and metastasis than existing models.