Metal-nanoparticle-involved chemiluminescence and its applications in bioassays
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- 作者：Na Li (2)
Danqing Liu (1)
Hua Cui (1) - 关键词：Metal nanoparticles ; Chemiluminescence ; Mechanism ; Bioassay
- 刊名：Analytical and Bioanalytical Chemistry
- 出版年：2014
- 出版时间：September 2014
- 年：2014
- 卷：406
- 期：23
- 页码：5561-5571
- 全文大小：671 KB
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Danqing Liu (1)
Hua Cui (1)
2. State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Chengdu University of Technology, Chengdu, 610059, Sichuan, China
1. CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, 230026, Anhui, China - ISSN：1618-2650
文摘
Chemiluminescence-based bioassays have become increasingly important in clinical, pharmaceutical, environmental, and food safety fields owing to their high sensitivity, wide linear range, and simple instrumentation. During the past decade, it has been found that metal nanoparticles can initiate various liquid-phase chemiluminescence reactions as catalysts, reductants, energy acceptors, and nanosized reaction platforms owing to their unique optical, catalytic, and surface properties and chemical reactivity, which are very important for chemiluminescence bioassays based on metal nanoparticles as nanoprobes or a nanointerface. In this article, we summarize recent progress in metal-nanoparticle-initiated liquid-phase chemiluminescence, including reaction systems, mechanisms, and their applications in chemiluminescence-based bioassays, especially for immunoassays, DNA assays, aptamer-based assays, high-performance liquid chromatography or capillary electrophoresis analysis, and flow injection analysis. Figure Comprehensive summary of metal nanoparticle (NP)-involved chemiluminescence (CL) systems and their applications. CE capillary electrophoresis, HPLC highperformance liquid chromatography