The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells
详细信息 查看全文
- 作者：Deguang Mu ; Wei Zhang ; Dongling Chu ; Tonggang Liu ; Yonghong Xie ; Enqing Fu and Faguang Jin
- 关键词：Dihydroartemisinin ; PC ; 14 cell ; Intracellular calcium concentration ; p38 MAPK ; Apoptosis
- 刊名：Cancer Chemotherapy and Pharmacology
- 出版年：2008
- 出版时间：April, 2008
- 年：2008
- 卷：61
- 期：4
- 页码：639-645
- 全文大小：393.2 KB
文摘
Introduction Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin isolated from the traditional Chinese herb Artemisia annua, is an effective novel antimalarial drug. Recent studies suggest that it also has anticancer effect.