Kavalactone content and chemotype of kava beverages prepared from roots and rhizomes of Isa and Mahakea varieties and extraction efficiency of kavalactones using different solvents
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- 作者：Jun Wang (1) (2)
Weiyue Qu (2)
Harry C. Bittenbender (3) (4)
Qing X. Li (2) (5)
1. Key Laboratory of Aquatic Botany and Watershed Ecology ; Wuhan Botanical Garden ; Chinese Academy of Sciences ; Wuhan ; 430074 ; China
2. Department of Molecular Biosciences and Bioengineering ; University of Hawaii at Manoa ; Honolulu ; HI ; 96822 ; USA
3. Department of Tropical Plant and Soil Sciences ; University of Hawaii at Manoa ; Honolulu ; HI ; 96822 ; USA
4. Department of Tropical Plant and Soil Sciences ; University of Hawaii ; 3190 Maile Way ; St. John 102 ; Honolulu ; HI ; 96822 ; USA
5. Department of Molecular Biosciences and Bioengineering ; University of Hawaii ; 1955 East-west Road ; Honolulu ; HI ; 96822 ; USA - 关键词：Piper methysticum ; Kava ; Kavalactone ; Chemotype ; Extraction efficiency
- 刊名：Journal of Food Science and Technology
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：52
- 期：2
- 页码：1164-1169
- 全文大小：688 KB
- 参考文献：1. Anke J, Ramzan I (2004) Kava hepatotoxicity: are we any closer to the truth? Planta Med 70:193鈥?96 CrossRef
2. Anon (2001) Medicines Control Agency Meeting, London UK, December 2001
3. Baum SS, Hill R, Rommelspacher H (1998) Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats. Prog Neuropsychopharmacol Biol Physchiatry 22:1105鈥?120 CrossRef
4. British Herbal Medicine Association鈥檚 Scientific Committee (1996) British herbal pharmacopoeia, 4th edn. BHMA, Bournemouth, pp 28鈥?9
5. Bilia AR, Gallori S, Vincieri FF (2002) Kava鈥搆ava and anxiety: growing knowledge about the efficacy and safety. Life Science 70:2581鈥?597 CrossRef
6. Brauer RB, Stangl M, Stewart JR, Pfab R, Becker K (2003) Acute liver failure after administration of the herbal tranquilliser kava-kava. J Clin Psychiatry 64:216鈥?18 CrossRef
7. Campo JV, McNabb J, Perel JM, Mazariegos GV, Hasegawa SL, Reyes J (2002) Kava-induced fulminant hepatic failure. J Am Acad Child Adolesc Psychiatry 41:631鈥?32 CrossRef
8. Dragull K, Yoshida WY, Tang CS (2003) Piperidine alkaloids from Piper methysticum. Phytochem 63:193鈥?98 CrossRef
9. Gow PJ, Connelly NJ, Hill RL, Crowley P, Angus PW (2003) Fatal fulminant hepatic failure induced by a natural therapy containing kava. Med J Australia 178:442鈥?43
10. Kilham C (1996) Kava: medicine hunting in paradise. Park Street Press Publisher, Rochester, p 166
11. Lebot V, L茅vesque J (1989) The origin and distribution of Kava (Piper methysticum Forst. f., Piperaceae): a phytochemical approach. National Tropical Botanical Garden, Hawaii Allertonia 5:223鈥?80
12. Lebot V, Merlin M, Lindstrom L (1992) Kava: the pacific drug. Psychoactive plants of the world series. Yale University Press, New Haven, p 260
13. Lebot V, L茅vesque J (1996a) Genetic control of kavalactone chemotypes in Piper methysticum cultivars. Phytochem 43:397鈥?03 CrossRef
14. Lebot V, L茅vesque J (1996b) Evidence for cospecificity of Piper methysticum Forst. f. and Piper wichmannii C. DC. Biochem Sys Ecol 24(7/8):775鈥?82
15. Lebot V, Johnston E, Zheng QY, McKern D, McKenna DJ (1999) Morphological, phytochemical, and genetic variation in Hawaiian cultivars of鈥檃wa (kava, Piper methysticum, Piperaceae). Eco Botany 53:407鈥?18 CrossRef
16. Russmann S, Lauterburg BH, Helbling A (2001) Kava hepatotoxicity. Ann Intern Med 135:68鈥?9 CrossRef
17. Schulz V, Hansel R, Tyler V (2001) Rational phytotherapy, a physician鈥檚 guide to herbal medicine, 4th edn. Springer, Germany, pp 172鈥?73 CrossRef
18. Singh S (1999) Variability of kavalactone content of yaqona samples in Fiji. M.Sc. Dissertation thesis, School of Pure and Applied Sciences, University of the South Pacific, Suva, Fiji
19. Singh YN (1992) Kava: an overview. J Ethnopharmacol 37:13鈥?5 CrossRef
20. Singh YN, Devkota AK (2003) Aqueous kava extracts do not affect liver function tests in rats. Planta Med 69:496鈥?99 CrossRef
21. Sim茅oni P, Lebot V (2002) Identification of factors determining kavalactone content and chemotype in Kava (Piper methysticum Forst. f.). Biochem Sys and Ecol 30:413鈥?24 CrossRef
22. Smith RM, Thakrar H, Arowolo TA, Safi AA (1984) High performance liquid chromatography of kava lactones from / Piper methysticum. J Chromatogr 283:303鈥?08 CrossRef
23. Smith RM (1983) Kava lactones in Piper methysticum from Fiji. Phytochem 22:1055鈥?056 CrossRef
24. Teschke R, Lebot V (2011) Proposal for a kava quality standardization code. Food Chem Toxicol 49:2503鈥?516 CrossRef
25. Wang J, Jun S, Bittenbender HC, Li QX (2010) Rapid determination of six kavalactones in kava root and rhizome samples using Fourier Transform infrared spectroscopy and multivariate analysis in comparison with gas chromatography. Anal Methods 2:492鈥?98 CrossRef
26. Whitton PA, Laua A, Salisburyb A, Whitehousec J, Evansd CS (2003) Kava lactones and the kava-kava controversy. Phytochem 64:673鈥?79 CrossRef - 刊物类别：Chemistry and Materials Science
- 刊物主题：Chemistry
Nutrition
Food Science
Chemistry - 出版者：Springer India
- ISSN：0975-8402
文摘
The South Pacific islanders have consumed kava beverage for thousands of years. The quality of kava and kava beverage is evaluated through determination of the content of six major kavalactones including methysticin, dihydromethysticin, kavain, dihydrokavain, yangonin and desmethoxyyangonin. In this study, we determined contents of kavalactones in and chemotype of kava beverages prepared from roots and rhizomes of Isa and Mahakea varieties and extraction efficiency of five different solvents including hexane, acetone, methanol, ethanol and ethyl acetate. The six major kavalactones were detected in all kava beverages with these five solvents. Different solvents had different extraction efficiencies for kavalactones from the lyophilized kava preparations. The contents of kavalactones in the extracts with acetone, ethanol, and methanol did not differ significantly. Ethanol had the highest extraction efficiency for the six major kavalactones whereas hexane gave the lowest extraction efficiency.