Inflammation and the Silent Sequelae of Stroke

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• 作者：Kyra J. Becker
• 关键词：Depression ; Fatigue ; Inflammation ; Stroke
• 刊名：Neurotherapeutics
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：13
• 期：4
• 页码：801-810
• 全文大小：744 KB
• 刊物主题：Neurosciences; Neurology; Neurosurgery; Neurobiology;
• 出版者：Springer US
• ISSN：1878-7479
• 卷排序：13

文摘

Depression and fatigue are common after stroke and negatively impact the quality of life of stroke survivors. The biological bases of these symptoms are unknown, but an abundance of data point to a role for inflammation. This review highlights evidence supporting the contribution of inflammation to poststroke depression and poststroke fatigue. Potential treatments for poststroke depression and poststroke fatigue are explored, with a special emphasis on those that modulate the immune response.