Serum trans fatty acids, asymmetric dimethylarginine and risk of acute myocardial infarction and mortality in patients with suspected coronary heart disease: a prospective cohort study
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- 作者：Heidi Borgeraas ; Jens Kristoffer Hertel ; Reinhard Seifert…
- 关键词：Acute myocardial infarction ; Asymmetric dimethylarginine ; Cardiovascular disease ; Mortality ; Trans fatty acid
- 刊名：Lipids in Health and Disease
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：15
- 期：1
- 全文大小：460 KB
- 刊物主题：Lipidology; Medical Biochemistry;
- 出版者：BioMed Central
- ISSN：1476-511X
文摘
Background Trans fatty acids (TFAs) have been found to impair flow mediated vasodilation and nitric oxide (NO) production. We sought to examine if serum TFA levels are associated with plasma levels of the NO inhibitor asymmetric dimethylarginine (ADMA) and if possible relationships between serum TFA and cardiovascular morbidity or mortality are mediated or modified by plasma ADMA levels.