Novel terpolymers of poly(p-dioxanone-co-trimethylene carbonate-co-L-phenylalanine): Synthesis, characterization, thermal properties and copolymerization mechanism

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• 作者：Li-nan Li ; Cheng-dong Xiong ; Dong-liang Chen 陈栋栿/a>
• 关键词：Terpolymers ; p ; Dioxanone ; Trimethylene carbonate ; L ; Phenylalanine ; Mechanism
• 刊名：Chinese Journal of Polymer Science
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：34
• 期：5
• 页码：594-605
• 全文大小：795 KB
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• 作者单位：Li-nan Li (1) (2)
  Cheng-dong Xiong (1)
  Dong-liang Chen 陈栋梁 (1)
  
  1. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China
  2. University of Chinese Academy of Sciences, Beijing, 100049, China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Condensed Matter Physics
  Industrial Chemistry and Chemical Engineering
  Polymer Sciences
  Characterization and Evaluation of Materials
  
• 出版者：Chinese Chemical Society and Institute of Chemistry, CAS, co-published with Springer
• ISSN：1439-6203

文摘

In order to exploit the biological functions of materials, a series of new random terpolymers were synthesized by the ring-opening polymerization of p-dioxanone, trimethylene carbonate, and L-phenylalanine N-carboxyanhydride (L-Phe- NCA) in the presence of stannous octoate. The terpolymers were characterized by 1H-NMR, 13C-NMR, FTIR, and gel permeation chromatography. The effects of the reactant ratio, catalyst dosage, reaction temperature and time on the copolymerization were investigated, and were found to regulate the composition of the terpolymer. Increases in the reaction temperature, polymerization time, L-Phe-NCA monomer amount, and catalyst content generated a product with a slightly decreased molecular weight. The crystallinity of the terpolymer was investigated by differential scanning calorimetry and polarized optical microscopy. A reasonable mechanism for the polymerization was proposed based on the obtained results.