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Testicular desmoplastic small round cell tumor: a case report and review of literature
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  • 作者:Gui-Ming Zhang (8) (9)
    Yao Zhu (8)
    Hua-Lei Gan (10)
    Ding-Wei Ye (8)

    8. Department of Urology
    ; Fudan University Shanghai Cancer Center ; No.270 ; Dongan Rd ; Shanghai ; 200032 ; China
    9. Department of Oncology
    ; Shanghai Medical College ; Fudan University ; Shanghai ; China
    10. Department of Pathology
    ; Fudan University Shanghai Cancer Center ; Shanghai ; China
  • 关键词:Desmoplastic small round cell tumor ; Testis ; Immunohistochemistry ; Chemotherapy
  • 刊名:World Journal of Surgical Oncology
  • 出版年:2014
  • 出版时间:December 2014
  • 年:2014
  • 卷:12
  • 期:1
  • 全文大小:728 KB
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  • 刊物主题:Surgical Oncology;
  • 出版者:BioMed Central
  • ISSN:1477-7819
文摘
Background Desmoplastic small round cell tumor (DSRCT) is an uncommon and highly aggressive malignancy with undetermined histogenesis and poor prognosis. To date, no case of testicular DSRCT has been reported in the literature. Case A 42-year-old Chinese man presented with painless swelling of his left testis and a painless palpable nodule in his left inguinal region. Computed tomography showed a solid mass in the left testis and multiple metastases in the body. Laboratory tests gave no abnormal results. Left radical orchiectomy was performed, and histopathological and molecular pathological examination showed typical features of DSRCT. Six cycles of chemotherapy were administrated after the operation, leading to partial remission. Postoperative 9-month follow-up indicated no progression.

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