Promoting effect of hepatitis B virus on the expressoin of phospholipase A2 group IIA
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- 作者：Chengliang Zhu ; Hui Song ; Bingzheng Shen ; Long Wu ; Fang Liu…
- 关键词：Hepatitis B virus ; Phospholipase A2 group IIA ; Chronic hepatitis B ; Liver cirrhosis ; Hepatocellular carcinoma
- 刊名：Lipids in Health and Disease
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：16
- 期：1
- 全文大小：1134KB
- 刊物主题：Lipidology; Medical Biochemistry; Clinical Nutrition;
- 出版者：BioMed Central
- ISSN：1476-511X
- 卷排序：16
文摘
BackgroundHepatitis B virus (HBV) infection causes acute and chronic liver disease, ultimately leading to the development of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Phospholipase A2 group IIA (PLA2G2A) plays important roles in the development and progression of many tumors. Thus far, there have been no reports on the association between HBV and PLA2G2A. The present study investigated the effect of HBV infection on PLA2G2A expression and its application in the diagnosis of HBV-related diseases.