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Repeated early hemofiltration filters clotting and heparin-induced thrombocytopenia in ICU
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  • 作者:Sébastien Perbet ; Thomas Godet…
  • 关键词:Heparin ; induced thrombocytopenia ; Hemofiltration ; Anti ; PF4 ; Diagnosis ; 4T’s score
  • 刊名:Journal of Clinical Monitoring and Computing
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:29
  • 期:1
  • 页码:25-28
  • 全文大小:369 KB
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    2. Greinacher A, Warkentin TE. Recognition, treatment, and prevention of heparin-induced thrombocytopenia: review and update. Thromb Res. 2006;118:165-6. CrossRef
    3. Warkentin TE, Linkins LA. Non-necrotizing heparin-induced skin lesions and the 4T’s score. J Thromb Haemost JTH. 2010;8:1483-. CrossRef
    4. Davies JO, Patel P, Zoumot Z. Diagnosing heparin induced thrombocytopenia in critically ill patients. Intensive Care Med. 2010;36:1447-. CrossRef
    5. Williamson DR, Albert M, Heels-Ansdell D, et al. Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest. 2013;144:1207-5. CrossRef
    6. Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A. Evaluation of pretest clinical score (4 T’s) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost JTH. 2006;4:759-5. CrossRef
    7. Warkentin TE, Sheppard JA, Moore JC, Moore KM, Sigouin CS, Kelton JG. Laboratory testing for the antibodies that cause heparin-induced thrombocytopenia: how much class do we need? J Lab Clin Med. 2005;146:341-. CrossRef
    8. Selleng S, Malowsky B, Strobel U, et al. Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive. J Thromb Haemost JTH. 2010;8:30-. CrossRef
    9. Zhao D, Sun X, Yao L, et al. The clinical significance and risk factors of anti-platelet factor 4/heparin antibody on maintenance hemodialysis patients: a two-year prospective follow-up. PLoS ONE. 2013;8:e62239. CrossRef
    10. Warkentin TE, Greinacher A, Gruel Y, et al. Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis. J Thromb Haemost JTH. 2011;9:2498-00. CrossRef
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    12. Warkentin TE, Hayward CP, Smith CA, Kelly PM, Kelton JG. Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia. J Lab Clin Med. 1992;120:371-.
    13. Lasocki S, Piednoir P, Ajzenberg N, Geffroy A, Benbara A, Montravers P. Anti-PF4/heparin antibodies associated with repeated hemofiltration-filter clotting: a retrospective study. Crit Care. 2008;12:R84. CrossRef
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    16. Godet T, Perbet S, Lebreton A, et al. Low Molecular Weight Heparin Induced Skin Necrosis without Platelet Fall Revealing Immunoallergic Heparin Induced Thrombocytopenia. Case Reports in
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Anesthesiology
    Intensive and Critical Care Medicine
    Statistics for Life Sciences, Medicine and Health Sciences
  • 出版者:Springer Netherlands
  • ISSN:1573-2614
文摘
Repeated early hemofiltration filter clotting are real thrombotic events. Diagnosis of heparin-induced thrombocytopenia (HIT) in this setting in ICU remains difficult. We describe two cases of repeated early hemofiltration filters clotting in ICU and to evaluate their impact on the probability test 4T’s score and diagnosis of HIT. Two patients undergoing at least three repeated early hemofiltration clotting filters in

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