Glycosaminoglycans from chicken muscular stomach or gizzard

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• 作者：Yin Chen ; Megan Reddy ; Yanlei Yu ; Fuming Zhang&#8230
• 关键词：Glycosaminoglycans ; Compositional analysis ; Heparan sulfate ; Chondroitin sulfate ; Hyaluranan ; Chicken gizzard
• 刊名：Glycoconjugate Journal
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：34
• 期：1
• 页码：119-126
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biochemistry, general; Pathology;
• 出版者：Springer US
• ISSN：1573-4986
• 卷排序：34

文摘

Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (~64 %) of molecular weight 21–22 kDa. Hyaluronan (~24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.