Regional myocardial microvascular dysfunction in cardiac amyloid light-chain amyloidosis: assessment with 3T cardiovascular magnetic resonance
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- 作者：Rui Li ; Zhi-gang Yang ; Lin-yi Wen ; Xi Liu…
- 关键词：Amyloid light ; chain cardiac amyloidosis ; Cardiovascular magnetic resonance ; Perfusion imaging ; Left ventricular function ; Coronary microvascular function
- 刊名：Journal of Cardiovascular Magnetic Resonance
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：2,758 KB
- 刊物主题：Imaging / Radiology; Angiology; Cardiology;
- 出版者：BioMed Central
- ISSN：1532-429X
- 卷排序：18
文摘
BackgroundCoronary microvascular dysfunction is highly prevalent in patients with amyloid light-chain (AL) cardiac amyloidosis (AL-CA). The aim of this study was to clarify the feasibility of first-pass perfusion imaging using 3 T cardiovascular magnetic resonance (CMR) for evaluating the difference in left ventricular (LV) regional myocardial microvascular function among normal subjects and in patients with AL-CA. The amyloidosis patients were classified into those with impaired systolic function [LV ejection fraction (LVEF) < 50 %] and those with preserved systolic function.