Biochemical parameters of renal impairment/injury and surrogate markers of nephron number in intrauterine growth-restricted and preterm neonates at 30–40 days of postnatal corrected age

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• 作者：Maria Cristina Aisa ; Benito Cappuccini ; Antonella Barbati…
• 关键词：Low birth weight ; Nephron number ; N ; acetyl ; β ; D ; glucosaminidase ; Cathepsin B ; Proteinuria ; 3D ; ultrasound imaging
• 刊名：Pediatric Nephrology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：31
• 期：12
• 页码：2277-2287
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Pediatrics; Nephrology; Urology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-198X
• 卷排序：31

文摘

BackgroundPremature and/or intrauterine growth-restricted neonates have an increased risk of developing postnatal renal injuries in later life. Studies on renal physiology in these neonates at a corrected age of 30–40 days are scarce and mostly relate to preterm infants. The data from these studies often lack the results of correlation analyses between biochemical parameters and nephron number—data which could provide additional insight and/or improve recognition of individuals at higher risk of renal failure.