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The tens of thousands of lives saved by randomized clinical trials in critical care
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  • 作者:Gordon S. Doig (1) (4)
    Ian Roberts (2)
    Rinaldo Bellomo (3)

    1. Northern Clinical School Intensive Care Research Unit
    ; University of Sydney ; Sydney ; Australia
    4. Level 6
    ; Intensive Care Unit ; Royal North Shore Hospital ; Pacific Hwy ; St Leonards ; NSW ; 2065 ; Australia
    2. Clinical Trials Unit
    ; London School of Hygiene and Tropical Medicine ; Keppel Street ; London ; UK
    3. School of Public Health and Preventive Medicine
    ; Monash University ; Melbourne ; VIC ; Australia
  • 刊名:Intensive Care Medicine
  • 出版年:2015
  • 出版时间:April 2015
  • 年:2015
  • 卷:41
  • 期:4
  • 页码:701-704
  • 全文大小:283 KB
  • 参考文献:1. Ibsen, B (1954) The anaesthetist鈥檚 viewpoint on the treatment of respiratory complications in poliomyelitis during the epidemic in Copenhagen, 1952. Proc R Soc Med 47: pp. 72-74
    2. Lassen, HC (1953) A preliminary report on the 1952 epidemic of poliomyelitis in Copenhagen with special reference to the treatment of acute respiratory insufficiency. Lancet 1: pp. 37-41 CrossRef
    3. Kumar, A, Roberts, D, Wood, KE, Light, B, Parrillo, JE, Sharma, S (2006) Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 34: pp. 1589-1596 CrossRef
    4. Willoughby, RE, Tieves, KS, Hoffman, GM, Ghanayem, NS, Amlie-Lefond, CM, Schwabe, MJ (2005) Survival after treatment of rabies with induction of coma. N Engl J Med 352: pp. 2508-2514 CrossRef
    5. Campos, T (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 342: pp. 1301-1308 CrossRef
    6. Dellinger, RP, Levy, MM, Rhodes, A, Annane, D, Gerlach, H, Opal, SM (2013) Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensiv Care Med 39: pp. 165-228 CrossRef
    7. Levy, MM, Rhodes, A, Phillips, GS, Townsend, SR, Schorr, CA, Beale, R (2014) Surviving sepsis campaign: association between performance metrics and outcomes in a 7.5-year study. Intensiv Care Med 40: pp. 1623-1633 CrossRef
    8. Roberts, I, Yates, D, Sandercock, P, Farrell, B, Wasserberg, J, Lomas, G (2004) Effect of intravenous corticosteroids on death within 14 days in 10,008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet 364: pp. 1321-1328 CrossRef
    9. Edwards, P, Arango, M, Balica, L, Cottingham, R, El-Sayed, H, Farrell, B (2005) Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury鈥攐utcomes at 6 months. Lancet 365: pp. 1957-1959 CrossRef
    10. Wiedemann, HP, Wheeler, AP, Bernard, GR, Thompson, BT, Hayden, D, deBoisblanc, B (2006) Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 354: pp. 2564-2575 CrossRef
    11. Maitland, K, Kiguli, S, Opoka, RO, Engoru, C, Olupot-Olupot, P, Akech, SO (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364: pp. 2483-2495 CrossRef
    12. Bellomo, R, Cass, A, Cole, L, Finfer, S, Gallagher, M, Lo, S (2009) Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 361: pp. 1627-1638 CrossRef
    13. Bellomo, R, Cass, A, Cole, L, Finfer, S, Gallagher, M, Lee, J (2012) An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial. Crit Care Med 40: pp. 1753-1760 CrossRef
  • 刊物主题:Intensive / Critical Care Medicine; Anesthesiology; Emergency Medicine; Pneumology/Respiratory System; Pain Medicine; Pediatrics;
  • 出版者:Springer Berlin Heidelberg
  • ISSN:1432-1238
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