Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China

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• 作者：Bo-feng Zhu ; Guang Yang ; Chun-mei Shen ; Hai-xia Qin ; Shuan-liang Fan ; Li-bin Deng ; Feng Chen ; Li-ping Chen ; Hong-dan Wang and Zhen-yuan Wang ; et al.
• 关键词：Russian population ; STR ; Population genetics
• 刊名：Molecular Biology Reports
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：37
• 期：8
• 页码：3889-3895
• 全文大小：260.1 KB

文摘

In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.