Ectopic breast tissue in axillary lymph node

详细信息    查看全文

• 作者：Masami Kadowaki (1)
  Takeshi Nagashima (1)
  Hiroto Sakata (1)
  Masahiro Sakakibara (1)
  Takafumi Sangai (1)
  Rikiya Nakamura (1)
  Hiroshi Fujimoto (1)
  Manabu Arai (1)
  Yasuhide Onai (1)
  Yuichirou Nagai (2)
  Yukimasa Miyazawa (1)
  Masaru Miyazaki (1)
  
• 关键词：Breast ; Ectopic tissue ; Lymph node ; Calcification ; Sentinel
• 刊名：Breast Cancer
• 出版年：2007
• 出版时间：October 2007
• 年：2007
• 卷：14
• 期：4
• 页码：425-428
• 全文大小：1388KB
• 参考文献：1. Fisher CJ, Hill S, Millis RR: Benign lymph node inclusions mimicking metastatic carcinoma. / J Clin Pathol 47:245鈥?47, 1994. CrossRef
  2. EdlowW D, Carter D: Heterotopic epithelium in axillary lymph nodes. / Am J Clin Pathol 59:666鈥?73, 1972.
  3. Holdsworth PJ, Hopkinson MJ, Leveson HS: Benign axillary lymph node inclusions - a histological pitfall. / Histopathology 13:226鈥?28, 1988. CrossRef
  4. Yaziji H, Gown AM: Detection of stromal invasion in breast cancer; the myoepithelial markers. / Adv Anat Pathol 7:100鈥?09, 2000. CrossRef
  5. Maiorano E, Mazzarol MG, Pruneri G, Mastropasqua MG, Zurrida S, Orvieto E, Viale G: Ectopic breast tissue as a possible cause of false-positive axillary sentinel lymph node biopsy. / Am J Surg Pathol 27:513鈥?18, 2003. CrossRef
  6. Turner DR, Millis RR: Breast tissue inclusions in axillary lymph nodes. / Histopathology 4:631鈥?36, 1980. CrossRef
  7. Carter AB, Jensen AR, Simpson FJ, Page DL: Benign transport of breast epithelium into axillary lymph nodes after biopsy. / Am J Clin Pathol 113:259鈥?65, 2000. CrossRef
  8. Rosen PP: Rozen鈥檚 breast pathology, 2nd ed, Lippincott Williams & Wilkins, Philadelphia: pp913鈥?22, 2001.
  9. Migliorini L: Proliferative intraductal lesion arising in ectopic breast tissue within axillary lymph node. / Histopathology 48:316, 2006. CrossRef
  10. Walker AN, Fechner RE: Papillary carcinoma arising from ectopic breast tissue in an axillary lymph node. / Diagn Gynecol Obset 4:141鈥?45, 1982.
  11. Kono S, Kurosumi M: Nipple adenoma found in a mastectomy specimen; report of a case with special regard to the proliferation pattern. / Breast cancer 14:234鈥?38, 2007. CrossRef
  
• 作者单位：Masami Kadowaki (1)
  Takeshi Nagashima (1)
  Hiroto Sakata (1)
  Masahiro Sakakibara (1)
  Takafumi Sangai (1)
  Rikiya Nakamura (1)
  Hiroshi Fujimoto (1)
  Manabu Arai (1)
  Yasuhide Onai (1)
  Yuichirou Nagai (2)
  Yukimasa Miyazawa (1)
  Masaru Miyazaki (1)
  
  1. Department of General Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, 260-0856, Chuo-ku, Chiba, Japan
  2. Molecular Pathology, Chiba University Graduate School of Medicine, Japan
  

文摘

Benign epithelial inclusions are uncommonly found in lymph nodes, and ectopic breast tissue in axillary lymph nodes is particularly uncommon. The patient is a 48-year-old woman who had an adenoma of the nipple removed 10 years previously. A swollen lymph node with amorphous calcifications in a clustered distribution on mammogram was found in the left axilla. Fine needle aspiration cytology showed only cystic change. Excisional biopsy was performed and microscopic examination demonstrated that the node contained benign mammary epithelial and glandular inclusions, and no evidence of malignancy. Such cases will be increasingly found due to the widespread use of mammography screening and biopsy of axillary sentinel lymph nodes. Ectopic breast tissue in lymph nodes may be mistaken for malig-nant lesions. It is most important to identify correctly the epithelial inclusions in lymph nodes to prevent an erroneous diagnosis.