One-step synthesis of 5-ethyl-2-methylpyridine from NH4HCO3 and C2H5OH under hydrothermal condition

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• 作者：Zhenzhen Tian (1)
  Dong Zhang (2)
  Biao Guo (1)
  Ge Tian (1)
  Xinxin Liu (1)
  Huijuan Yue (1)
  Shouhua Feng (1)
  
  1. State Key Laboratory of Inorganic Synthesis and Preparative Chemistry ; College of Chemistry ; Jilin University ; Changchun ; 130012 ; P. R. China
  2. Key Laboratory of Physics and Technology for Advance Batteries ; Ministry of Education ; College of Physics ; Jilin University ; Changchun ; 130012 ; P. R. China
  
• 关键词：5 ; Ethyl ; 2 ; methylpyridine ; Hydrothermal condition ; NH4HCO3 ; C2H5OH ; Cu2O
• 刊名：Chemical Research in Chinese Universities
• 出版年：2015
• 出版时间：April 2015
• 年：2015
• 卷：31
• 期：2
• 页码：249-252
• 全文大小：493 KB
• 参考文献：1. Baumann, M, Baxendale, I R (2013) Beilstein J. Org. Chem. 9: pp. 2265 CrossRef
  2. Krishna Mohan, K V V, Narender, N (2012) Catal. Sci. Technol. 2: pp. 471 CrossRef
  3. Dunn, J T (1955) Process for Marking Substituted Pyridines.
  4. Nenz, A, Pieroni, M (1968) Hydrocarb. Process 47: pp. 139
  5. Bespalov, K P, Antonov, V V, Promonenkov, V K (1980) Osnovn Organ Sintez I Neftekhimiya 13: pp. 58
  6. Olah, G A, Arvanaghi, M, Vankar, Y D (1980) Synthesis 8: pp. 660 CrossRef
  7. Yusupov, D, Israilov, R I, Kuchkarov, A B (1992) Doklady Akademii Nauk Respubliki Uzbekistan 1: pp. 34
  8. Sirlibaev, T S, Nurmanov, S E (1991) Izvestiya Vysshikh Uchebnykh Zavehenii: Khimiya i Khimicheskaya Tekhnologiya 34: pp. 102
  9. Liepinya, I M, Sile, M K, Avots, A A, Lazdinsh, I Y (1984) React. Kinet. Catal. Lett. 26: pp. 123 CrossRef
  10. Selimov, F A, Akhmetov, A Z, Dzhemilev, U M (1987) Bull. Acad. Sci. USSR 36: pp. 1893 CrossRef
  11. Rosas, C B, Wantuck, J A, Kaufman, A (1974) Process for the Production of 2-Methyl-5-ethylpyridine.
  12. Swider, E W (1960) Continuous Production of 2-Methyl-5-ethylpyridine.
  13. Krishna Mohan, K V V, Suresh Kumar Reddy, K, Narender, N, Kulkarni, S J (2009) J. Mol. Catal. A 298: pp. 99 CrossRef
  14. Chichibabin, A E (1937) Bull. Soc. Chim. 4: pp. 1831
  15. Graf, R (1938) Journal F眉r Praktische Chemie 150: pp. 153 CrossRef
  16. Frank, R L, Blegen, J R, Dearborn, R J, Myers, R L, Woodward, F E (1946) J. Am. Chem. Soc. 68: pp. 1368 CrossRef
  17. Schnizer Arthur, W, Stautzenberger Adin, L (1958) Production of 2-Methyl-5-ethylpyridine.
  18. Shimizu, S, Abe, N, Iguchi, A, Dohba, M, Sato, H, Hirose, K (1998) Micropor. Mesopor. Mater. 21: pp. 447 CrossRef
  19. Ramachandra Rao, R, Kulkarni, S J, Subrahmanyam, M, Rama Rao, A V (1995) React. Kinet. Catal. Lett. 56: pp. 301 CrossRef
  20. Kulkarni, S J, Ramachandra Rao, R, Subrahmanyam, M, Rama Rao, A V (1995) React. Kinet. Catal. Lett. 56: pp. 291 CrossRef
  21. Rama Rao, A V, Kulkarni, S J, Ramachandra Rao, R, Subrahmanyam, M (1994) Appl. Catal. A 111: pp. L101 CrossRef
  22. Wang, Y, Feng, S H (2014) Chem. J. Chinese Universities 35: pp. 707
  23. Tian, G, Yuan, H M, Mu, Y, He, C, Feng, S H (2007) Org. Lett. 9: pp. 2019 CrossRef
  24. Wang, Y L, Tan, D X (2014) Chem. Res. Chinese Universities 30: pp. 320 CrossRef
  25. Sagitullin, R S, Shkil, G P, NosonovA, I I, Ferber, A A (1996) Chem. Heterocycl. Compd. 32: pp. 127 CrossRef
  
• 刊物主题：Chemistry/Food Science, general; Analytical Chemistry; Inorganic Chemistry; Organic Chemistry; Physical Chemistry;
• 出版者：Springer Berlin Heidelberg
• ISSN：2210-3171

文摘

A simple one-pot approach to synthesizing 5-ethyl-2-methylpyridine(EMP) was established using NH4HCO3 and C2H5OH as starting materials and commercial Cu2O as catalyst and oxidant under hydrothermal condition. Different reaction conditions were researched and the optimal ones were achieved by studying the parameters, that could affect the yield of product and by considering the energy and resource saving. The present study provided an eco-friendly way to obtaining EMP with lower volatility using fewer toxic starting materials.