Complete genome sequence of a sapovirus from a child in Zhejiang, China

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• 作者：Xiaohong Zhou ; Yi Sun ; Xiaochun Shang ; Jian Gao ; Xueqin Zhao ; Huiqun Shuai…
• 关键词：Sapovirus ; Genome ; Phylogeny
• 刊名：Virus Genes
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：52
• 期：5
• 页码：706-710
• 全文大小：633 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Medical Microbiology
  Virology
  Plant Sciences
  
• 出版者：Springer Netherlands
• ISSN：1572-994X
• 卷排序：52

文摘

Although Sapovirus (Caliciviridae) has been accepted as one of the causes of acute gastroenteritis worldwide, little is known about the genetic characteristics of the whole genome of sapoviruses in China, especially those that infect humans. Here we report the complete genome sequence of a sapovirus strain, Human/Zhejiang1/2015/China, obtained from a child with acute gastroenteritis in Hangzhou, Zhejiang Province, China. Samples were collected and delivered to the CDC laboratories and were detected by RT-PCR. Sanger sequencing was used to obtain the full genome and molecular characterization of the genome was determined. A phylogenetic analysis of the genome was also performed. The results indicated that Human/Zhejiang1/2015/China belongs to Genogroup I. No recombination events were detected. This is the first complete sequence from a child to be reported in China. The sequence information is important for surveillance of this emerging gastrointestinal infection.