文摘
Controlled fabrication of biocompatible nanofibers with the required nanoscale and electrical performance can meet the needs of practical applications in biomedicine and electrochemistry. Here we report a high-performance 3D electroconductive nanomaterial templated by biocompatible bacterial cellulose (BC) nanofibers. Our approach can coat BC nanofibers with poly(3,4-ethylenedioxythiophene) (PEDOT) by in situ interfacial polymerization in a controllable manner, with average nanofiber diameters of 30-00 nm. PSS (poly(styrene sulfonate)) was doped to improve its conductivity in a controlled way. Mechanical performance and electrochemical measurements showed that the composite possesses excellent electroactive and mechanical stability. Especially evidence was provided that the BC/PEDOT nanofibers with moderate PSS doping had excellent biocompatibility according to the results concerning the cellular morphology and proliferation of human mesenchymal stem cells cultured on the BC/PEDOT/PSS nanofibers. As a 3D conductive nanomaterial with flexibility, it shows potential application in electroactive substrates/scaffolds for tissue engineering, cell culture, biosensors, drug delivery and implanted electrodes. Keywords Controllable fabrication 3D nanofibers Bacterial cellulose Biocompatible Electroconductive Templated