Human gut microbiota: the links with dementia development
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- 作者：Rashad Alkasir ; Jing Li ; Xudong Li ; Miao Jin ; Baoli Zhu
- 关键词：dementia ; alzheimer’s disease ; gut microbiota ; inflammation ; probiotics
- 刊名：Protein & Cell
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：8
- 期：2
- 页码：90-102
- 全文大小：938KB
- 刊物主题：Biochemistry, general; Protein Science; Cell Biology; Stem Cells; Human Genetics; Developmental Biology;
- 出版者：Higher Education Press
- ISSN：1674-8018
- 卷排序：8
文摘
Dementia is a comprehensive category of brain diseases that is great enough to affect a person’s daily functioning. The most common type of dementia is Alzheimer’s disease, which makes most of cases. New researches indicate that gastrointestinal tract microbiota are directly linked to dementia pathogenesis through triggering metabolic diseases and low-grade inflammation progress. A novel strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of dementia and other related diseases through modulation of the microbiota (e.g. with the use of probiotics).