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The Effect of Fatal Carbon Monoxide Poisoning on the Equilibria Between Cell Membranes and the Electrolyte Solution
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  • 作者:Aneta D. Petelska ; Joanna Kotyńska
  • 关键词:Acid–base equilibria ; Surface charge density ; Microelectrophoresis ; Erythrocytes ; Thrombocytes ; Fatal carbon monoxide poisoning
  • 刊名:Journal of Membrane Biology
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:248
  • 期:1
  • 页码:157-161
  • 全文大小:276 KB
  • 参考文献:1. Alexander AE, Johnson P (1949) Colloid science. Clarendon Press, Oxford
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    3. Dobrzyńska I, Skrzydlewska E, Figaszewski Z (2006) Parameters characterizing acid–base equilibria between cell membrane and solution and their application to monitoring the effect of various factors on the membrane. Bioelectrochemistry 69:142-47 CrossRef
    4. Dobrzyńska I, Kotyńska J, Figaszewski Z (2007) Changes in electrical charge of phosphatidylcholine and phosphatidylserine liposomal membranes caused by adsorption of monovalent ions. Chem Anal 52:931-44
    5. Hauck H, Neuberger M (1984) Carbon monoxide uptake and the resulting carboxyhemoglobin in man. Eur J Appl Physiol Occup Physiol 53:186-90 CrossRef
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    7. Kotyńska J, Dobrzyńska I, Figaszewski Z (2008) Effect of monovalent ion adsorption on the electric charge of phosphatidylcholine–decylamine liposomal membranes. J Bioenerg Biomembr 40:637-41 CrossRef
    8. Kotyńska J, Petelska AD, Szeremeta M, Niemcunowicz-Janica A, Figaszewski ZA (2012) Changes in surface charge density of blood cells after sudden unexpected death. J Membr Biol 245:185-90 CrossRef
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    11. Omaye ST (2002) Metabolic modulation of carbon monoxide toxicity. Toxicology 180:139-50 CrossRef
    12. Petelska AD, Janica JR, Kotyńska J, ?ebkowska U, Figaszewski ZA (2012) The effect of contrast medium SonoVue? on the electric charge density of blood cells. J Membr Biol 245:15-2 CrossRef
    13. Sawyer WR, Steup DR, Martin BS, Forney RB (1988) Cardiac blood pH as a possible indicator of postmortem interval. J Forensic Sci 33(1988):1439-444
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    16. Szachowicz-Petelska B, Dobrzyńska I, Skrzydlewska E, Figaszewski ZA (2008) Changes in phospholipid composition studied by HPLC and electric properties of liver cell membrane of ethanol-poisoned rats. Toxicol Mech Method 18:525-30 CrossRef
    17. Szachowicz-Petelska B, Dobrzynska I, Sulkowski S, Figaszewski ZA (2010) Characterization of the cell membrane during cancer transformation. J Environ Biol 31:845-850
    18. Szachowicz-Petelska B, Dobrzyńska I, Figaszewski ZA, Kudelski J (2014) Changes in the physico-chemical properties of human kidney cell membranes during the cancer transformation. Adv Biol Chem 4:223-31 CrossRef
    19. Szeremeta M, Petelska AD, Kotyńska J, Niemcunowicz-Janica A, Figaszewski ZA (2013) The effect of fatal carbon monoxide poisoning on the surface charge of blood cells. J Membr Biol 246:467-71 CrossRef
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  • 作者单位:Aneta D. Petelska (1)
    Joanna Kotyńska (1)
    Zbigniew A. Figaszewski (1) (2)

    1. Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443, Bia?ystok, Poland
    2. Laboratory of Electrochemical Power Sources Faculty of Chemistry, University of Warsaw, Pasteur St. 1, 02-093, Warsaw, Poland
  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Life Sciences
    Biochemistry
    Human Physiology
  • 出版者:Springer New York
  • ISSN:1432-1424
文摘
The effect of fatal carbon monoxide poisoning on equilibria between cell membranes and surrounding ions was described using a theoretical four-equilibria model. The model was developed to obtain parameters characterizing the interactions between solution ions and erythrocyte or thrombocyte membrane surface. The parameters are the total surface concentrations of both acidic and basic groups C A, C B and their association constants with solution ions K AH, K BOH. These parameters were used to calculate the theoretical values of surface charge density. The model was validated by comparison of these values to experimental data, which were determined from the electrophoretic mobility measurements of the blood cells. The experimental and theoretical surface charge density values agree at pH 2-, and at higher pH, the deviation was observed.

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