The role of electrostatic interactions in the process of diffusional encounter and docking of electron transport proteins

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• 作者：I. B. Kovalenko ; S. S. Khrushchev ; V. A. Fedorov…
• 刊名：Doklady Biochemistry and Biophysics
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：468
• 期：1
• 页码：183-186
• 全文大小：186 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Biochemistry
  Biophysics and Biomedical Physics
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3091
• 卷排序：468

文摘

Electrostatic interaction of plastocyanin and cytochrome f in the process of protein–protein complex formation was investigated by computer simulation methods. It was shown that long-range electrostatic interaction promotes energetically favorable mutual orientation of protein molecules at distances between their cofactors shorter than 5 nm. At distances shorter than 3 nm, these electrostatic interactions lead to a significantly detectable increase in the rate of convergence of the cofactors.Original Russian Text © I.B. Kovalenko, S.S. Khrushchev, V.A. Fedorov, G.Yu. Riznichenko, A.B. Rubin, 2016, published in Doklady Akademii Nauk, 2016, Vol. 468, No. 2, pp. 220–224.