Laparoscopic versus open splenectomy and devascularization for massive splenomegaly due to portal hypertension

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• 作者：Yao Liu 刘 尧 ; Long Zhao 赵 龙 ; Yong Tang 唐 勇…
• 关键词：massive splenomegaly ; portal hypertension ; laparoscopy ; splenectomy ; devascularization
• 刊名：Journal of Huazhong University of Science and Technology [Medical Sciences]
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：36
• 期：6
• 页码：876-880
• 全文大小：
• 刊物主题：Medicine/Public Health, general;
• 出版者：Huazhong University of Science and Technology
• ISSN：1993-1352
• 卷排序：36

文摘

Although the clinical benefit of laparoscopic splenectomy and devascularization (LSD) has been elaborated in many studies, its application in massive splenomegaly remains controversial. We conducted a retrospective research to assess the curative efficacy of LSD for massive splenomegaly due to portal hypertension. Forty-seven patients with massive splenomegaly due to portal hypertension were enrolled in this study, and divided into two groups. Twenty-one patients underwent open splenectomy and devascularization (OSD) from June 2010 to October 2012 (OSD group). From March 2013 to February 2015, LSD was performed on 26 patients (LSD group). Perioperative variables were analyzed. Compared to OSD, LSD was associated with less blood loss (241.9±110.0 mL vs. 319.0±139.5 mL, P<0.05), more rapid resumption of oral diet (2.46±0.95 days vs. 3.76±1.09 days, P<0.05), and shorter postoperative hospital stay (5.35±1.65 days vs. 7.24±1.55 days, P<0.05). It was concluded that for patients with massive splenomegaly due to portal hypertension, LSD is feasible and as safe as OSD.