Probiotic mixture improves fatty liver disease by virtue of its action on lipid profiles, leptin, and inflammatory biomarkers
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- 作者：Hessah Mohammed Al-muzafar ; Kamal Adel Amin
- 关键词：Probiotics ; HFSD ; Lipid profile ; Leptin ; Inflammation ; NAFLD biomarkers
- 刊名：BMC Complementary and Alternative Medicine
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：846KB
- 刊物主题：Complementary & Alternative Medicine; Internal Medicine; Chiropractic Medicine;
- 出版者：BioMed Central
- ISSN：1472-6882
- 卷排序：17
文摘
BackgroundA high fat diet has an essential role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). This condition is characterized by hepatic fat accumulation (steatosis) and is associated with obesity, diabetes, and fibrosis or cirrhosis of the liver. Probiotics may be useful in the treatment of steatosis. This study examined the effects of an ingested probiotic formulation on the lipid profiles, liver functions, leptin levels, and inflammatory marker levels of rats with NAFLD that had been induced via high fat and sucrose diet (HFSD).