Microbial production of 2,3-butanediol by a newly-isolated strain of Serratia marcescens
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- 作者：Litao Shi (1)
Songsong Gao (1)
Yue Yu (1)
Hongjiang Yang (1) - 关键词：Acetoin ; Aeration rate ; 2 ; 3 ; Butanediol ; Diol production ; Serratia marcescens
- 刊名：Biotechnology Letters
- 出版年：2014
- 出版时间：May 2014
- 年：2014
- 卷：36
- 期：5
- 页码：969-973
- 全文大小：242 KB
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Songsong Gao (1)
Yue Yu (1)
Hongjiang Yang (1)
1. Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China - ISSN：1573-6776
文摘
A newly-isolated strain of Serratia marcescens, G12, was characterized for 2,3-butanediol (2,3-BD) production. In shake-flask and batch fermentations, 2,3-BD reached 48.5 and 51?g?l?, respectively. Low amounts of (~8?g?l?) of acetoin were also formed. In fed-batch fermentations, strain G12 produced 72.8?g 2,3-BD?l? with glucose initially at 130?g?l?. When aeration rate was increased to 2.5?vvm for the fermentation process, 2,3-BD reached 87.8?g?l? and the highest productivity was 1.6?g?l??h?. Acetoin was at 6.2?g?l?. G12 therefore may be a suitable candidate strain for large-scale production of 2,3-BD.