Weight loss versus muscle loss: re-evaluating inclusion criteria for future cancer cachexia interventional trials

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• 作者：Eric J. Roeland ; Joseph D. Ma ; Sandahl H. Nelson…
• 关键词：Cachexia ; Cancer ; Muscle loss ; Weight loss ; Interventional trials
• 刊名：Supportive Care in Cancer
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：25
• 期：2
• 页码：365-369
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology; Nursing; Nursing Research; Pain Medicine; Rehabilitation Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1433-7339
• 卷排序：25

文摘

PurposeParticipation in cancer cachexia clinical trials requires a defined weight loss (WL) over time. A loss in skeletal muscle mass, measured by cross-sectional computed tomography (CT) image analysis, represents a possible alternative. Our aim was to compare WL versus muscle loss in patients who were screened to participate in a cancer cachexia clinical trial.