Altered fractional amplitude of low frequency fluctuation associated with cognitive dysfunction in first-episode drug-naïve major depressive disorder patients

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• 作者：Manli Huang ; Shaojia Lu ; Liang Yu ; Lingjiang Li ; Peng Zhang ; Jianbo Hu…
• 关键词：Major depressive disorder ; Cognitive function ; Fractional amplitude of low frequency fluctuation (fALFF)
• 刊名：BMC Psychiatry
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：2877KB
• 刊物主题：Psychiatry; Psychotherapy;
• 出版者：BioMed Central
• ISSN：1471-244X
• 卷排序：17

文摘

BackgroundPrevious studies have demonstrated that abnormities of both resting-state brain activity and cognitive dysfunction are frequently observed in patients with major depressive disorder (MDD). However, the underlying relationship between these two aspects is less investigated. In this context, the aim of the present study was to investigate the association between cognitive dysfunction and altered resting-state brain function in first-episode drug-naïve MDD patients.