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Characteristic patterns of the longitudinal and circumferential distribution of calcium deposits by parent coronary arteries observed from computed tomography angiography
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  • 作者:Shoichi Ehara ; Kenji Matsumoto ; Takao Hasegawa ; Kenichiro Otsuka…
  • 关键词:Calcium ; Coronary artery ; Computed tomography ; Atherosclerosis
  • 刊名:Heart and Vessels
  • 出版年:2016
  • 出版时间:April 2016
  • 年:2016
  • 卷:31
  • 期:4
  • 页码:508-518
  • 全文大小:1,656 KB
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  • 作者单位:Shoichi Ehara (1)
    Kenji Matsumoto (1)
    Takao Hasegawa (1)
    Kenichiro Otsuka (1)
    Mikumo Sakaguchi (1)
    Kenei Shimada (1)
    Junichi Yoshikawa (2)
    Minoru Yoshiyama (1)

    1. Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan
    2. Nishinomiya Watanabe Cardiovascular Center, Nishinomiya, Hyogo, Japan
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Cardiology
    Cardiac Surgery
    Vascular Surgery
    Biomedical Engineering
    Interventional Radiology
    Ultrasound
  • 出版者:Springer Japan
  • ISSN:1615-2573
文摘
Many investigators have reported that the total amount of coronary calcium correlates with the overall magnitude of atherosclerotic plaque burden in the entire coronary tree and is a powerful predictor of future cardiovascular events. However, the development and spatial distribution of coronary calcifications remain unclear. We investigated the spatial distribution of calcifications throughout the coronary tree during coronary artery evaluation using coronary computed tomography angiography (CTA). A further aim was to assess the progression of existing calcifications and the development of new deposits in a follow-up study. The study population consisted of 287 patients for the cross-sectional study using CTA to evaluate the spatial distribution of calcifications by parent coronary arteries. Next, we analyzed a CTA dataset of 57 patients who had undergone two CTA examinations. In this group, the two CTA images were used for assessing the progression of existing calcifications and the development of new deposits. The coronary calcifications tended to be clustered within the proximal and middle portions. Moreover, in the proximal left anterior descending coronary artery (LAD), small calcifications were located more toward the inner pericardial side. Finally, new calcium deposits developed within the proximal and middle portions of the LAD and left circumflex coronary artery, but those in the right coronary artery were likely to appear evenly from the proximal to the distal portion. This study shows the characteristic patterns of the longitudinal and circumferential distribution of calcifications by parent coronary arteries.

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