The effect of a dietary supplement (N-oleyl-phosphatidyl-ethanolamine and epigallocatechin gallate) on dietary compliance and body fat loss in adults who are overweight: A double-blind, randomized control trial
详细信息 查看全文
- 作者：Gerald T Mangine (1)
Adam M Gonzalez (1)
Adam J Wells (1)
William P McCormack (1)
Maren S Fragala (1)
Jeffrey R Stout (1)
Jay R Hoffman (1) - 关键词：Dietary Adherence ; Appetite ; Obesity ; Green Tea Extract
- 刊名：Lipids in Health and Disease
- 出版年：2012
- 出版时间：December 2012
- 年：2012
- 卷：11
- 期：1
- 全文大小：213KB
- 参考文献：1. Flegal KM, Carroll MD, Ogden CL, Curtin LR:
2. National Center for Health Statistics:
3. Willett WC, Manson JE, Stampfer MJ, Colditz GA, Rosner B, Speizer FE, Hennekens CH:
4. Yusuf S, Hawken S, Ounpuu S, Bautista L, Franzosi MG, Commerford P, Lang CC, Rumboldt Z, Onen CL, Lisheng L, / et al.:
5. Colditz GA, Willett WC, Rotnitzky A, Manson JE:
6. Ray CS, Sue DY, Bray G, Hansen JE, Wasserman K:
7. Janssen I:
8. Andreou E, Philippou C, Papandreou D:
9. Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, Napoli N, Qualls C, Shah K:
10. Carels RA, Young KM, Coit C, Clayton AM, Spencer A, Hobbs M:
11. Makris A, Foster GD:
12. Arterburn D, Noel PH:
13. Barratt R, Frost G, O’Boyle A, Millward J, Truby H:
14. Ioannides-Demos LL, Proietto J, McNeil JJ:
15. Perrio MJ, Wilton LV, Shakir SA:
16. Manore MM:
17. Rondanelli M, Opizzi A, Solerte SB, Trotti R, Klersy C, Cazzola R:
18. Williams CM, Kirkham TC:
19. Fu J, Gaetani S, Oveisi F, Lo Verme J, Serrano A, Rodriguez De Fonseca F, Rosengarth A, Luecke H, Di Giacomo B, Tarzia G, Piomelli D:
20. Overton HA, Babbs AJ, Doel SM, Fyfe MC, Gardner LS, Griffin G, Jackson HC, Procter MJ, Rasamison CM, Tang-Christensen M, / et al.:
21. Chantre P, Lairon D:
22. Nagao T, Hase T, Tokimitsu I:
23. Wang H, Wen Y, Du Y, Yan X, Guo H, Rycroft JA, Boon N, Kovacs EM, Mela DJ:
24. Zhu BT, Shim JY, Nagai M, Bai HW:
25. Borchardt RT, Huber JA:
26. Bose M, Lambert JD, Ju J, Reuhl KR, Shapses SA, Yang CS:
27. Lonac MC, Richards JC, Schweder MM, Johnson TK, Bell C:
28. Broccali GBM, Pistolesi E, Cestaro B:
29. Board FN: / Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). USA: The National Academies Press; 2002. [ / Book Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients)]
30. Hoffman J: / Norms for fitness, performance, and health. USA: Human Kinetics, New Jersey; 2006.
31. Glickman SG, Marn CS, Supiano MA, Dengel DR:
32. Katrina K, King N, Hayes D: / Moving Away From Diets: Healing Eating Problems and Exercise Resistance. Texas, USA: Helm Publishing & Seminars; 2003.
33. McNair D, Lorr M, Droppleman LF: / Profile of Mood States Manual, Book Profile of Mood States Manual. San Diego, CA: Educational and Industrial Testing Service; 1971.
34. Gormally J, Black S, Daston S, Rardin D:
35. Bingham SA, Cassidy A, Cole TJ, Welch A, Runswick SA, Black AE, Thurnham D, Bates C, Khaw KT, Key TJ, / et al.:
36. Hebert JR, Clemow L, Pbert L, Ockene IS, Ockene JK:
37. Ahern GP:
38. Aviello G, Matias I, Capasso R, Petrosino S, Borrelli F, Orlando P, Romano B, Capasso F, Di Marzo V, Izzo AA:
39. Capasso R, Matias I, Lutz B, Borrelli F, Capasso F, Marsicano G, Mascolo N, Petrosino S, Monory K, Valenti M, / et al.:
40. Thomas DM, Bouchard C, Church T, Slentz C, Kraus WE, Redman LM, Martin CK, Silva AM, Vossen M, Westerterp K, Heymsfield SB: / Why do individuals not lose more weight from an exercise intervention at a defined dose?. Obes Rev: An energy balance analysis; 2012.
41. King NA, Horner K, Hills AP, Byrne NM, Wood RE, Bryant E, Caudwell P, Finlayson G, Gibbons C, Hopkins M, / et al.:
42. Wadden TA, Foster GD, Sarwer DB, Anderson DA, Gladis M, Sanderson RS, Letchak RV, Berkowitz RI, Phelan S:
43. Sherwood NE, Jeffery RW, Wing RR:
44. Brown AL, Lane J, Coverly J, Stocks J, Jackson S, Stephen A, Bluck L, Coward A, Hendrickx H:
45. Wightman EL, Haskell CF, Forster JS, Veasey RC, Kennedy DO:
46. Suganuma M, Okabe S, Oniyama M, Tada Y, Ito H, Fujiki H:
47. Paladini AC, Marder M, Viola H, Wolfman C, Wasowski C, Medina JH:
48. Adachi N, Tomonaga S, Tachibana T, Denbow DM, Furuse M:
49. Vignes M, Maurice T, Lante F, Nedjar M, Thethi K, Guiramand J, Recasens M:
50. Steptoe A, Gibson EL, Vuononvirta R, Williams ED, Hamer M, Rycroft JA, Erusalimsky JD, Wardle J: - 作者单位：Gerald T Mangine (1)
Adam M Gonzalez (1)
Adam J Wells (1)
William P McCormack (1)
Maren S Fragala (1)
Jeffrey R Stout (1)
Jay R Hoffman (1)
1. Sport and Exercise Science, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL, 32816, USA
文摘
Background A dietary supplement containing a blend of 170?mg of N-oleyl-phosphatidylethanolamine (NOPE) and 100?mg of epigallocatechin-3-gallate (EGCG) has been shown to improve compliance to low caloric diets. Considering the cost of dietary ingredients, many manufacturers attempt to determine the lowest efficacious dose. Thus, the purpose of this study was to evaluate the efficacy of 8-weeks of supplementation with a daily intake of 120?mg of NOPE and 105?mg of EGCG in conjunction with a low caloric diet and regular, moderate exercise on dietary compliance in healthy, overweight adults. An additional purpose was to examine the effect of this supplement/diet/exercise paradigm on changes in body composition, sensation of appetite, mood and severity of binge eating. Methods Fifty healthy, overweight (BMI-gt;-5?m·kg2) men (15) and women (35) (SUP; n--5; 32.7?±-3.75 y; BMI--3.4?±-.2; PLA; n--5, 34.3?±-2.7?years; BMI--3.2?±-.8) were recruited for a double-blind, placebo controlled study. Each volunteer was randomly assigned to either the supplement (SUP; n--5) or placebo group (PLA; n--5). Based upon a self-reported 3-day dietary recall all volunteers were recommended a 500?kcal or 30% (maximum of 1000?kcal) reduction in caloric intake. Volunteers were also encouraged to exercise 30?minutes per day, three times per week. Results Subjects in SUP were significantly more compliant (x 2--.86, p--.049) in maintaining a low caloric diet at week 4, but this was not able to be maintained through the 8-week study. In addition, a significant difference in mood, feelings of fatigue and confusion were noted between the groups at week 4, but again not maintained by week 8 where only feelings of tension were improved. No differences between groups (p-gt;-.05) were observed for body mass, body composition, feelings of hunger, and binge eating after eight weeks. Conclusion Supplementing with a combination of 120?mg of NOPE and 105?mg of EGCG does appear to enhance compliance to a low caloric diet and improve mood for 4 –weeks, but loses its effectiveness by week 8.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |