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Peculiarities of methemoglobin recovery system in erythrocytes of sterlet under nitrite intoxication
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  • 作者:L. V. Khuda ; O. I. Khudyi ; M. M. Marchenko
  • 关键词:nitrite ; methemoglobin ; erythrocytes ; sterlet Acipenser ruthenus L.
  • 刊名:Inland Water Biology
  • 出版年:2015
  • 出版时间:April 2015
  • 年:2015
  • 卷:8
  • 期:2
  • 页码:195-199
  • 全文大小:110 KB
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    8.Khuda, L.V., Marchenko, M.M., Khachman, Ya.Yu., and Khudii, O.I., Effect of nitric intoxication on the methemoglobin recovery system in erythrocytes of silver carp, Biol. Sist., 2012, vol. 4, no. 4, pp. 393鈥?96.
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  • 作者单位:L. V. Khuda (1)
    O. I. Khudyi (1)
    M. M. Marchenko (1)

    1. Fedkovych National University, Chernivtsi, Ukraine
  • 刊物主题:Freshwater & Marine Ecology; Biodiversity; Geoecology/Natural Processes;
  • 出版者:Springer US
  • ISSN:1995-0837
文摘
The content of methemoglobin and the functional status of its recovery system in erythrocytes have been studied for the sterlet Acipenser ruthenus L. exposed to a sodium nitrite concentration ranging from 7.25 to 217.5 mmol/L. The functional features of methemoglobin reductase system form the basis of the specific accumulation of methemoglobin. High concentrations of nitrite in plasma inhibit hemo-containing enzymes (methemoglobin reductase and catalase) that normally prevent the excessive accumulation of methemoglobin. Under the conditions of nitrite intoxication, the leading role in the functioning of the methemoglobin reduction system belongs to its nonenzymatic components (reduced glutathione and ascorbate).

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