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Role of MexA-MexB-OprM efflux pump system in chronic Pseudomonas Aeruginosa pulmonary infection in mice
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  • 作者:Fengyun Gong (1)
    Weili Zhan (1)
    Lili Wang (2)
    Ying Song (1)
    Mingyou Xing (1)
    Jianxin Song (1)
  • 关键词:Pseudomonas aeruginosa ; MexA ; MexB ; OprM efflux pump ; pulmonary infections ; MexB ; antibacterial resistance
  • 刊名:Journal of Huazhong University of Science and Technology [Medical Sciences]
  • 出版年:2012
  • 出版时间:August 2012
  • 年:2012
  • 卷:32
  • 期:4
  • 页码:546-551
  • 全文大小:674KB
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    2. Higgins PG, Fluit AC, Milatovic D, / et al. Antimicrobial susceptibility of imipenem-resistant / Pseudomonas aerugi nosa. Antimicrob Agents Chemother, 2002,50(2): 299-01 CrossRef
    3. Mesaros N, Nordmann P, Roussel-Delvallez M, / et al. Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium. Clin Microbiol Infect, 2007,13(6):560-78 CrossRef
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    6. Kriengkauykiat J, Porter E, Lomovskaya O, / et al. Use of an efflux pump inhibitor to determine the prevalence of efflux pump-mediated fluoroquinolone resistance and multidrug resistance in / Pseudomonas aeruginosa. Antimicrob Agents Chemother, 2005,49(2):565-70 CrossRef
    7. Kukavica-Ibrulj I, Bragozi A, Paroni M, / et al. In vivo growth of / Pseudomonas aeruginosa strains PAO1 and PA14 and the hypervirulent strain LESB58 in a rat model of chronic lung infection. J Bacteriol, 2008,190(8): 2804-813 CrossRef
    8. Maria MD, Borrell N, Perez JL, / et al. Detection and susceptibility testing of hypermutable / Pseudomonas aeruginosa strains with the E test and disk diffusion. Antimicrob Agents Chemother, 2004,48(7):2665-672 CrossRef
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    15. Li XZ, Nikaido H, Poole K, / et al. Role of MexA-MexB-OprM in antibiotic efflux in / Pseudomonas aeruginosa. Antimicrob Agents Chemother, 1995,39(9):1948-953 CrossRef
    16. Vojtová V, Kolár M, Uvízl R, / et al. Antibiotic utilization and / Pseudomonas aeruginosa resistance in intensive care units. New Microbiol, 2011,34(3):291-98
    17. Li XZ, Barré. N, Poole K, / et al. Influence of the MexA-MexB-OprM multidrug efflux system on expression of the MexC-MexD-OprJ and MexE-MexF-OprN multidrug efflux systems in / Pseudomonas aeruginosa. J Antimicrob Chemother, 2000,46(6):885-93 CrossRef
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  • 作者单位:Fengyun Gong (1)
    Weili Zhan (1)
    Lili Wang (2)
    Ying Song (1)
    Mingyou Xing (1)
    Jianxin Song (1)

    1. Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
    2. Department of Respiratory Medicine, Central Hospital of Qingdao, Qingdao, 266042, China
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