High-Altitude Headache

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• 作者：Michael J. Marmura (1) (3)
  Pablo Bandres Hernandez (2)
  
  1. Department of Neurology ; Thomas Jefferson University ; Philadelphia ; PA ; USA
  3. Jefferson Headache Center ; Jefferson Hospital for Neuroscience ; 900 Walnut Street ; Suite 200 ; Philadelphia ; PA ; 19107 ; USA
  2. Department of Neurology ; Hospital Fundaci贸n Alcorc贸n ; Madrid ; Spain
  
• 关键词：High ; altitude headache ; Acute mountain sickness ; Hypoxia ; Pathophysiology
• 刊名：Current Pain and Headache Reports
• 出版年：2015
• 出版时间：May 2015
• 年：2015
• 卷：19
• 期：5
• 全文大小：799 KB
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• 刊物主题：Pain Medicine; Internal Medicine;
• 出版者：Springer US
• ISSN：1534-3081

文摘

High-altitude headache is one of many neurological symptoms associated with the ascent to high altitudes. Cellular hypoxia due to decreased barometric pressure seems to be the common final pathway for headache as altitude increases. Susceptibility to high-altitude headache depends on genetic factors, history of migraine, and acclimatization, but symptoms of acute mountain sickness are universal at very high altitudes. This review summarizes the pathophysiology of acute mountain sickness and high-altitude headache as well as the evidence for treatment and prevention with different drugs and devices which may be useful for regular and novice mountaineers. This includes an examination of other headache disorders which may mimic high-altitude headache.