Mucuna sanjappae Aitawade et Yadav: a new species of Mucuna with promising yield of anti-Parkinson’s drug L-DOPA

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• 作者：R. R. Patil ; A. R. Gholave ; J. P. Jadhav…
• 关键词：L ; DOPA ; Mucuna sanjappae ; Parkinson’s disease
• 刊名：Genetic Resources and Crop Evolution
• 出版年：2015
• 出版时间：January 2015
• 年：2015
• 卷：62
• 期：1
• 页码：155-162
• 全文大小：683 KB
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  23. Lowry OH,
• 作者单位：R. R. Patil (1) (2)
  A. R. Gholave (3)
  J. P. Jadhav (1) (2)
  S. R. Yadav (3)
  V. A. Bapat (2)
  
  1. Department of Biochemistry, Shivaji University, Kolhapur, 416 004, India
  2. Department of Biotechnology, Shivaji University, Vidyanagar, Kolhapur, 416 004, India
  3. Department of Botany, Shivaji University, Kolhapur, 416 004, India
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Plant Sciences
  Plant Physiology
  Plant Pathology
  
• 出版者：Springer Netherlands
• ISSN：1573-5109

文摘

Mucuna is a well-known medicinal and food plant widely exploited for its seed pods and leaves in many tropical countries. The drug L-3, 4-dihydroxyphenylalanine (L-DOPA) extracted from seeds of Mucuna plant has been commonly used in the treatment of Parkinson’s disease. In the present study, a new species of Mucuna, M. sanjappae Aitawade et Yadav from north-Western Ghats of India, has been analyzed for the presence of L-DOPA and a reasonable level of this drug (7.3?%) was detected. The necessary biochemical characterization of the seeds extract of this plant showed nutritional and anti-nutritional components. Simultaneously, moisture, ash, dietary fiber, calorific value, nitrate and mineral contents of seeds were also determined. This new plant species will be a potential candidate for extraction of L-DOPA and will be a good addition to the existing natural sources of anti-Parkinson’s drug since demand for L-DOPA is continuously escalating.