Association of Lipid Peroxidation and Brain-Derived Neurotrophic Factor with Executive Function in Adolescent Bipolar Disorder
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- 作者：Dwight F. Newton ; Melanie R. Naiberg ; Ana C. Andreazza ; Gustavo Scola…
- 关键词：Bipolar disorder ; Oxidative stress ; Brain ; derived neurotrophic factor ; Executive function ; Child and adolescent psychiatry
- 刊名：Psychopharmacology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：234
- 期：4
- 页码：647-656
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Neurosciences; Pharmacology/Toxicology; Psychiatry;
- 出版者：Springer Berlin Heidelberg
- ISSN：1432-2072
- 卷排序：234
文摘
BackgroundExecutive dysfunction is common and impairing in youth bipolar disorder (BD), and oxidative stress (OS) and brain-derived neurotrophic factor (BDNF) have been implicated in executive deficits of adult BD. This study aimed to determine the association between OS and executive dysfunction in BD adolescents and the influence of BDNF on this association.