Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases

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• 作者：Caroline Clausen (1)
  Lars L?nn (1) (2)
  S?ren Schmidt Morgen (3)
  Michael Bachmann Nielsen (4)
  Susanne Christiansen Frevert (1)
  P?r Ingemar Johansson (5) (6)
  Benny Dahl (3)
  
• 关键词：Spinal neoplasms ; Spinal metastases ; Spinal surgery ; Blood transfusion ; Survival ; Mortality
• 刊名：European Spine Journal
• 出版年：2014
• 出版时间：August 2014
• 年：2014
• 卷：23
• 期：8
• 页码：1791-1796
• 全文大小：166 KB
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• 作者单位：Caroline Clausen (1)
  Lars L?nn (1) (2)
  S?ren Schmidt Morgen (3)
  Michael Bachmann Nielsen (4)
  Susanne Christiansen Frevert (1)
  P?r Ingemar Johansson (5) (6)
  Benny Dahl (3)
  
  1. Section of Cardiovascular Radiology, Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark
  2. Department of Vascular Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  3. Spine Unit, Department of Orthopaedic Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  4. Section of Ultrasound, Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  5. Section of Transfusion Medicine, Department of Clinical Immunology, Capital Region Blood Bank, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  6. Department of Surgery, CeTIR, University of Texas Medical School at Houston, Houston, TX, USA
  
• ISSN：1432-0932

文摘

Purpose To assess whether perioperative allogenic blood transfusions in patients undergoing surgical treatment for spinal metastases independently influence patient survival. Methods A retrospective study including 170 consecutive patients undergoing surgical treatment for spinal metastases in 2009 and 2010 at a tertiary referral center. Variables related to postoperative survival were all included in the same multivariable logistic regression analysis with either 3- or 12-month survival as the dependent variable. The independent variables were: transfusion of allogenic red blood cells, age at surgery, gender, preoperative hemoglobin, revised Tokuhashi score and no. of instrumented levels. Results Perioperative allogenic blood transfusion of 1- units was associated with increased 12-month survival [p?=?0.049, odds ratio 2.619 (confidence interval 1.004-.831)], but not with 3-month survival. Larger transfusion volumes did not significantly influence survival. Conclusion The results of the present study support that perioperative blood transfusion of