Increased rates of protein evolution and asymmetric deceleration after the whole-genome duplication in yeasts
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- 作者：Diana Ascencio ; Soledad Ochoa ; Luis Delaye ; Alexander DeLuna
- 关键词：Gene duplication ; Whole ; genome duplication ; Protein ; evolution rate ; Purifying selection ; Asymmetric evolution ; Phylogenetic analysis by maximum likelihood ; Biological function ; Saccharomyces cerevisiae
- 刊名：BMC Evolutionary Biology
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：831KB
- 刊物主题：Evolutionary Biology; Animal Systematics/Taxonomy/ Biogeography; Entomology; Genetics and Population Dynamics; Life Sciences, general;
- 出版者：BioMed Central
- ISSN：1471-2148
- 卷排序：17
文摘
BackgroundWhole-genome duplication (WGD) events have shaped the genomes of eukaryotic organisms. Relaxed selection after duplication along with inherent functional constraints are thought to determine the fate of the paralogs and, ultimately, the evolution of gene function. Here, we investigated the rate of protein evolution (as measured by dN/dS ratios) before and after the WGD in the hemiascomycete yeasts, and the way in which changes in such rates relate to molecular and biological function.