Design optimization of stent and its dilatation balloon using kriging surrogate model
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- 作者：Hongxia Li ; Tao Liu ; Minjie Wang ; Danyang Zhao ; Aike Qiao…
- 关键词：Stent ; Fatigue life ; Dogboning effect ; Finite element method ; Kriging surrogate model ; Design optimization
- 刊名：BioMedical Engineering OnLine
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：16
- 期：1
- 全文大小：1747KB
- 刊物类别：Engineering
- 刊物主题：Biomedical Engineering; Biomaterials; Biotechnology; Biomedical Engineering/Biotechnology;
- 出版者：BioMed Central
- ISSN：1475-925X
- 卷排序：16
文摘
BackgroundAlthough stents have great success of treating cardiovascular disease, it actually undermined by the in-stent restenosis and their long-term fatigue failure. The geometry of stent affects its service performance and ultimately affects its fatigue life. Besides, improper length of balloon leads to transient mechanical injury to the vessel wall and in-stent restenosis. Conventional optimization method of stent and its dilatation balloon by comparing several designs and choosing the best one as the optimal design cannot find the global optimal design in the design space. In this study, an adaptive optimization method based on Kriging surrogate model was proposed to optimize the structure of stent and the length of stent dilatation balloon so as to prolong stent service life and improve the performance of stent.