Pronuclear removal of tripronuclear zygotes can establish heteroparental normal karyotypic human embryonic stem cells

详细信息    查看全文

• 作者：Hong-Qing Liao ; Qi OuYang ; Shuo-Ping Zhang…
• 关键词：Tripronuclear zygotes ; Pronuclear removal ; Blastocyst culture ; hESCs ; Heteroparental inheritance
• 刊名：Journal of Assisted Reproduction and Genetics
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：33
• 期：2
• 页码：255-263
• 全文大小：4,873 KB
• 参考文献：1.Pieters MH, Dumoulin JC, Ignoul-Vanvuchelen RC, Bras M, Evers JL, Geraedts JP. Triploidy after in vitro fertilization: cytogenetic analysis of human zygotes and embryos. J Assist Reprod Genet. 1992;9:68–76.CrossRef PubMed
  2.Rosenbusch BE. Selective microsurgical removal of a pronucleus from tripronuclear human oocytes to restore diploidy: disregarded but valuable? Fertil Steril. 2009;92:897–903. doi:10.​1016/​j.​fertnstert.​2008.​07.​1740 .CrossRef PubMed
  3.Porter R, Han T, Tucker MJ, Graham J, Liebermann J, Sills ES. Estimation of second polar body retention rate after conventional insemination and intracytoplasmic sperm injection: in vitro observations from more than 5000 human oocytes. J Assist Reprod Genet. 2003;20:371–6.PubMedCentral CrossRef PubMed
  4.Kang HJ, Rosenwaks Z. Triploidy—the breakdown of monogamy between sperm and egg. Int J Dev Biol. 2008;52:449–54. doi:10.​1387/​ijdb.​082602hk .CrossRef PubMed
  5.Plachot M, Crozet N. Fertilization abnormalities in human in-vitro fertilization. Hum Reprod. 1992;7 Suppl 1:89–94.CrossRef PubMed
  6.Staessen C, Van Steirteghem AC. The chromosomal constitution of embryos developing from abnormally fertilized oocytes after intracytoplasmic sperm injection and conventional in-vitro fertilization. Hum Reprod. 1997;12:321–7.CrossRef PubMed
  7.Grossmann M, Calafell JM, Brandy N, Vanrell JA, Rubio C, Pellicer A, et al. Origin of tripronucleate zygotes after intracytoplasmic sperm injection. Hum Reprod. 1997;12:2762–5.CrossRef PubMed
  8.Golubovsky MD. Postzygotic diploidization of triploids as a source of unusual cases of mosaicism, chimerism and twinning. Hum Reprod. 2003;18:236–42.CrossRef PubMed
  9.Rosenbusch BE. Mechanisms giving rise to triploid zygotes during assisted reproduction. Fertil Steril. 2008;90:49–55. doi:10.​1016/​j.​fertnstert.​2007.​06.​031 .CrossRef PubMed
  10.Zaragoza MV, Surti U, Redline RW, Millie E, Chakravarti A, Hassold TJ. Parental origin and phenotype of triploidy in spontaneous abortions: predominance of diandry and association with the partial hydatidiform mole. Am J Hum Genet. 2000;66:1807–20. doi:10.​1086/​302951 .PubMedCentral CrossRef PubMed
  11.McFadden DE, Robinson WP. Phenotype of triploid embryos. J Med Genet. 2006;43:609–12. doi:10.​1136/​jmg.​2005.​037747 .PubMedCentral CrossRef PubMed
  12.Berkowitz RS, Goldstein DP. Clinical practice molar pregnancy. N Engl J Med. 2009;360:1639–45. doi:10.​1056/​NEJMcp0900696 .CrossRef PubMed
  13.Rawlins RG, Binor Z, Radwanska E, Dmowski WP. Microsurgical enucleation of tripronuclear human zygotes. Fertil Steril. 1988;50:266–72.PubMed
  14.Gordon JW, Grunfeld L, Garrisi GJ, Navot D, Laufer N. Successful microsurgical removal of a pronucleus from tripronuclear human zygotes. Fertil Steril. 1989;52:367–72.PubMed
  15.Malter HE, Cohen J. Embryonic development after microsurgical repair of polyspermic human zygotes. Fertil Steril. 1989;52:373–80.PubMed
  16.Palermo G, Munne S, Cohen J. The human zygote inherits its mitotic potential from the male gamete. Hum Reprod. 1994;9:1220–5.PubMed
  17.Ivakhnenko V, Cieslak J, Verlinsky Y. A microsurgical technique for enucleation of multipronuclear human zygotes. Hum Reprod. 2000;15:911–6.CrossRef PubMed
  18.Escriba MJ, Martin J, Rubio C, Valbuena D, Remohi J, Pellicer A, et al. Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos. Fertil Steril. 2006;86:1601–7. doi:10.​1016/​j.​fertnstert.​2006.​04.​047 .CrossRef PubMed
  19.Gu Y-F, Lin G, Lu C-F, Lu G-X. Analysis of the first mitotic spindles in human in vitro fertilized tripronuclear zygotes after pronuclear removal. Reprod BioMed Online. 2009;19:745–54.CrossRef PubMed
  20.Kattera S, Chen C. Normal birth after microsurgical enucleation of tripronuclear human zygotes: case report. Hum Reprod. 2003;18:1319–22.CrossRef PubMed
  21.Gardner DK, Schoolcraft WB. No longer neglected: the human blastocyst. Hum Reprod. 1998;13:3289–92.CrossRef PubMed
  22.Jones GM, Trounson AO, Gardner DK, Kausche A, Lolatgis N, Wood C. Evolution of a culture protocol for successful blastocyst development and pregnancy. Hum Reprod. 1998;13:169–77.CrossRef PubMed
  23.Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145–7.CrossRef PubMed
  24.Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol. 2000;18:399–404. doi:10.​1038/​74447 .CrossRef PubMed
  25.Mitalipova M, Calhoun J, Shin S, Wininger D, Schulz T, Noggle S, et al. Human embryonic stem cell lines derived from discarded embryos. Stem Cells. 2003;21:521–6. doi:10.​1634/​stemcells.​21-5-521 .CrossRef PubMed
  26.Lavon N, Narwani K, Golan-Lev T, Buehler N, Hill D, Benvenisty N. Derivation of euploid human embryonic stem cells from aneuploid embryos. Stem Cells. 2008;26:1874–82. doi:10.​1634/​stemcells.​2008-0156 .CrossRef PubMed
  27.Lin G, OuYang Q, Zhou XY, Gu YF, Yuan D, Li W, et al. A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res. 2007;17:999–1007. doi:10.​1038/​cr.​2007.​97 .CrossRef PubMed
  28.Lin G, Xie Y, OuYang Q, Qian X, Xie P, Zhou X, et al. HLA-matching potential of an established human embryonic stem cell bank in China. Cell Stem Cell. 2009;5:461–5. doi:10.​1016/​j.​stem.​2009.​10.​009 .CrossRef PubMed
  29.Angell RR, Templeton AA, Messinis IE. Consequences of polyspermy in man. Cytogenet Cell Genet. 1986;42:1–7.CrossRef PubMed
  30.Kola I, Trounson A, Dawson G, Rogers P. Tripronuclear human oocytes: altered cleavage patterns and subsequent karyotypic analysis of embryos. Biol Reprod. 1987;37:395–401.CrossRef PubMed
  31.Rosenbusch B, Schneider M, Sterzik K. The chromosomal constitution of multipronuclear zygotes resulting from in-vitro fertilization. Hum Reprod. 1997;12:2257–62.CrossRef PubMed
  32.Iliopoulos D, Vassiliou G, Sekerli E, Sidiropoulou V, Tsiga A, Dimopoulou D, et al. Long survival in a 69, XXX triploid infant in Greece. Genet Mol Res. 2005;4:755–9.PubMed
  33.Clouston HJ, Fenwick J, Webb AL, Herbert M, Murdoch A, Wolstenholme J. Detection of mosaic and non-mosaic chromosome abnormalities in 6- to 8-day old human blastocysts. Hum Genet. 1997;101:30–6.CrossRef PubMed
  34.Evsikov S, Verlinsky Y. Mosaicism in the inner cell mass of human blastocysts. Hum Reprod. 1998;13:3151–5.CrossRef PubMed
  35.Magli MC, Jones GM, Gras L, Gianaroli L, Korman I, Trounson AO. Chromosome mosaicism in day 3 aneuploid embryos that develop to morphologically normal blastocysts in vitro. Hum Reprod. 2000;15:1781–6.CrossRef PubMed
  36.Sandalinas M, Sadowy S, Alikani M, Calderon G, Cohen J, Munne S. Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage. Hum Reprod. 2001;16:1954–8.CrossRef PubMed
  37.Liao H, Zhang S, Cheng D, Ouyang Q, Lin G, Gu Y, et al. Cytogenetic analysis of human embryos and embryonic stem cells derived from monopronuclear zygotes. J Assist Reprod Genet. 2009;26:583–9. doi:10.​1007/​s10815-009-9355-1 .PubMedCentral CrossRef PubMed
  38.Hardy K. Cell death in the mammalian blastocyst. Mol Hum Reprod. 1997;3:919–25.CrossRef PubMed
  39.Janny L, Menezo YJ. Maternal age effect on early human embryonic development and blastocyst formation. Mol Reprod Dev. 1996;45:31–7.CrossRef PubMed
  40.Fan Y, Li R, Huang J, Yu Y, Qiao J. Diploid, but not haploid, human embryonic stem cells can be derived from microsurgically repaired tripronuclear human zygotes. Cell Cycle. 2013;12:302–11. doi:10.​4161/​cc.​23103 .PubMedCentral CrossRef PubMed
  41.Jiang C, Cai L, Huang B, Dong J, Chen A, Ning S, et al. Normal human embryonic stem cell lines were derived from microsurgical enucleated tripronuclear zygotes. J Cell Biochem. 2013;114:2016–23. doi:10.​1002/​jcb.​24547 .CrossRef PubMed
  42.Fan Y, Li R, Huang J, Zhao HC, Ding T, Sun X, et al. Improved efficiency of microsurgical enucleated tripronuclear zygotes development and embryonic stem cell derivation by supplementing epidermal growth factor, brain-derived neurotrophic factor, and insulin-like growth factor-1. Stem Cells Dev. 2014;23:563–75. doi:10.​1089/​scd.​2013.​0420 .PubMedCentral CrossRef PubMed
  
• 作者单位：Hong-Qing Liao (1)
  Qi OuYang (2) (3)
  Shuo-Ping Zhang (2) (4)
  De-Hua Cheng (4)
  Guang-Xiu Lu (2) (3) (4)
  Ge Lin (2) (3) (4)
  
  1. The Second Affiliated Hospital of South China University, 30th Jie-Fang Road, Hengyang, Hunan, 421001, China
  2. Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, Hunan, 410078, China
  3. National Engineering and Research Center of Human Stem Cell, Changsha, Hunan, 410078, China
  4. CITIC-Xiangya Reproductive and Genetic Hospital, Changsha, Hunan, 410078, China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Gynecology
  Developmental Biology
  Human Genetics
  
• 出版者：Springer Netherlands
• ISSN：1573-7330

文摘

Purpose This study aimed to derive heteroparental normal karyotypic human embryonic stem cells (hESCs) from microsurgically corrected tripronuclear (3PN) zygotes.