Study on age-dependent pre-existing 2009 pandemic influenza virus T and B cell responses from Chinese population
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- 作者：Jin Lv ; Zhen-Yong Ren ; Ying-Ying Zhang ; Yun-E Liu ; Jun Gao…
- 关键词：Pandemic influenza ; Memory B cell ; IFN ; γ+ T cell ; ELISpot ; Age ; dependent
- 刊名：BMC Infectious Diseases
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：802KB
- 刊物主题：Infectious Diseases; Parasitology; Medical Microbiology; Tropical Medicine; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2334
- 卷排序：17
文摘
BackgroundThe outbreak of the 2009 H1N1 influenza pandemic (H1N1pdm) affected thousands of people in Mexico and the United States, and spread rapidly throughout the world from April 2009 to July 2010. To explore the age-specific prevalence of seroprotection against H1N1pdm infection, we estimated pre-existing humoral and cellular immunities of residents in Northern China against H1N1pdm and seasonal H1N1 virus in an age-dependent manner.