A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data
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- 作者：Henrik Engblom ; Jane Tufvesson…
- 关键词：LGE CMR ; Automatic quantification algorithm ; Expectation maximization ; Experimental validation ; Multi ; center patient data
- 刊名：Journal of Cardiovascular Magnetic Resonance
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：3,308 KB
- 刊物主题：Imaging / Radiology; Angiology; Cardiology;
- 出版者：BioMed Central
- ISSN：1532-429X
- 卷排序：18
文摘
BackgroundLate gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying results and advanced algorithms have only been validated in single center studies. Therefore, the aim of this study was to develop an automatic algorithm for MI quantification in IR and PSIR LGE images and to validate the new algorithm experimentally and compare it to expert delineations in multi-center, multi-vendor patient data.